Time to reconsider the role of donor hepatitis C status in the Kidney Donor Risk Index.
作者信息
Potluri Vishnu, Kulkarni Sanjay
机构信息
Renal-Electrolyte and Hypertension Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
出版信息
Am J Transplant. 2023 May;23(5):595-596. doi: 10.1016/j.ajt.2023.02.013. Epub 2023 Feb 10.
Abstract
摘要
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Time to reconsider the role of donor hepatitis C status in the Kidney Donor Risk Index.是时候重新审视供体丙型肝炎状态在肾脏供体风险指数中的作用了。
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Re: Impact of Donor Hepatitis C Virus on Kidney Transplant Outcomes for Hepatitis C-Positive Recipients in the Direct-Acting Antiviral Era: Time to Revise the Kidney Donor Risk Index?关于：在直接抗病毒药物时代，供体丙型肝炎病毒对丙型肝炎病毒阳性受者肾移植结局的影响：是时候修订肾脏供体风险指数了吗？
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Factors associated with hepatitis C antibody seroconversion after transplantation of kidneys from hepatitis C infected donors to hepatitis C naïve recipients.丙型肝炎感染供体的肾脏移植给未感染丙型肝炎的受体后，与丙型肝炎抗体血清转化相关的因素。
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Use of HCV Ab+/NAT- donors in HCV naïve renal transplant recipients to expand the kidney donor pool.利用 HCV Ab+/NAT- 供体进行 HCV 初治肾移植受者以扩大肾脏供体池。
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Transmission of viral hepatitis by kidney transplantation: donor evaluation and transplant policies (Part 2: hepatitis C virus).肾移植传播病毒性肝炎：供体评估与移植政策（第2部分：丙型肝炎病毒）
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The association of donor hepatitis C virus infection with 3-year kidney transplant outcomes in the era of direct-acting antiviral medications.直接作用抗病毒药物时代供体丙型肝炎病毒感染与 3 年肾移植结局的关系。
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Transplantation of hepatitis C virus (HCV) antibody positive, nucleic acid test negative donor kidneys to HCV negative patients frequently results in seroconversion but not HCV viremia.将丙型肝炎病毒 (HCV) 抗体阳性、核酸检测阴性的供体肾脏移植给 HCV 阴性患者，常导致血清转换，但不会引起 HCV 病毒血症。
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Are we underestimating the quality of aviremic hepatitis C-positive kidneys? Time to reconsider.我们是否低估了无 HCV RNA 血症的 HCV 阳性供肾的质量？是时候重新考虑了。
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Multivariable Predictors of Poorer Renal Function Among 1119 Deceased Donor Kidney Transplant Recipients During the First Year Post-Transplant, With a Particular Focus on the Influence of Individual KDRI Components and Donor AKI.1119例尸体供肾移植受者移植后第一年肾功能较差的多变量预测因素，特别关注个体KDRI成分和供体急性肾损伤的影响。
Clin Transplant. 2025 Apr;39(4):e70080. doi: 10.1111/ctr.70080.
本文引用的文献
1
The association of donor hepatitis C virus infection with 3-year kidney transplant outcomes in the era of direct-acting antiviral medications.直接作用抗病毒药物时代供体丙型肝炎病毒感染与 3 年肾移植结局的关系。
Am J Transplant. 2023 May;23(5):629-635. doi: 10.1016/j.ajt.2022.11.005. Epub 2023 Jan 12.
2
Five-Year Allograft Survival for Recipients of Kidney Transplants From Hepatitis C Virus Infected vs Uninfected Deceased Donors in the Direct-Acting Antiviral Therapy Era.直接作用抗病毒治疗时代，丙型肝炎病毒感染与未感染的已故供体肾移植受者的 5 年移植物存活率。
JAMA. 2022 Sep 20;328(11):1102-1104. doi: 10.1001/jama.2022.12868.
3
Survey of Clinician Opinions on Kidney Transplantation from Hepatitis C Virus Positive Donors: Identifying and Overcoming Barriers.临床医生对丙型肝炎病毒阳性供体肾移植的意见调查：识别和克服障碍。
Kidney360. 2020 Nov;1(11):1291-1299. doi: 10.34067/KID.0004592020. Epub 2020 Nov 25.
4
Exploring patient willingness to accept hepatitis C-infected kidneys for transplantation.探讨患者对接受丙型肝炎感染肾脏进行移植的意愿。
BMC Nephrol. 2020 Nov 10;21(1):473. doi: 10.1186/s12882-020-02114-y.
5
Reevaluation of the Kidney Donor Risk Index.重新评估肾脏供体风险指数。
Transplantation. 2019 Aug;103(8):1714-1721. doi: 10.1097/TP.0000000000002498.
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