Social Neuroscience Lab, Institute of Psychology, Polish Academy of Sciences, Poland.
Social Neuroscience Lab, Institute of Psychology, Polish Academy of Sciences, Poland.
J Psychiatr Res. 2022 Nov;155:85-89. doi: 10.1016/j.jpsychires.2022.07.069. Epub 2022 Aug 4.
Social cognitive deficits are currently considered as one of the main predictors of clinical symptoms and functional outcome in patients with schizophrenia. Multiple studies have suggested that a two-factor solution (low-level vs. high-level) best describes the structure of social cognitive processes in patients. While higher-order processes have been repeatedly linked to negative symptoms, no such association was found for lower-level processes. Thus, the aim of the current study is to examine whether the association between basic social perception processes and symptoms in patients with schizophrenia is mediated by mentalizing abilities. One hundred thirty-nine patients have completed basic social perception (Communicative Interactions Database task CID-12) and mentalizing (Reading the Mind in the Eyes task) tasks. In line with our hypothesis, we have observed full mediation of the effects of basic social perception abilities on negative symptoms via mentalizing abilities in patients. This effect suggests that, similarly as in the case of positive symptoms, a hierarchical nature of social cognitive processes should be considered while investigating negative symptoms of schizophrenia.
社会认知缺陷目前被认为是精神分裂症患者临床症状和功能结果的主要预测因素之一。多项研究表明，双因素模型（低水平与高水平）最能描述患者社会认知过程的结构。虽然高阶过程已被反复与阴性症状相关联，但在低水平过程中没有发现这种关联。因此，本研究旨在检验精神分裂症患者基本社会知觉过程与症状之间的关联是否通过心理化能力来介导。139 名患者完成了基本社会知觉（交际互动数据库任务 CID-12）和心理化（眼神阅读任务）任务。与我们的假设一致，我们观察到基本社会知觉能力对阴性症状的影响通过心理化能力在患者中完全中介。这种效应表明，类似于阳性症状的情况，在研究精神分裂症的阴性症状时，应该考虑社会认知过程的层次性质。
