萨希瓦尔牛（印度野牛）和卡兰弗莱牛（ × ）的乳房类型特征与单核苷酸多态性的关联。

Association of udder type traits with single nucleotide polymorphisms in Sahiwal (Bos indicus) and Karan Fries ( × ) cattle.

机构信息

ICAR-National Dairy Research Institute, Karnal, Haryana, India.

Department of Animal Genetics and Breeding, Faculty of Veterinary and Animal Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

出版信息

Anim Biotechnol. 2023 Dec;34(7):2745-2756. doi: 10.1080/10495398.2022.2114083. Epub 2022 Aug 24.

DOI:10.1080/10495398.2022.2114083

PMID:36001402

Abstract

Udder structure of milking cows is not merely vital to display the visual characteristics, but also important for high milk output and low mastitis risk incidence as well. The present study measured different udder type traits in Sahiwal () and Karan Fries () and investigated their association with single nucleotide polymorphisms in Vitamin D Receptor and Protein Tyrosine Phosphatase, Receptor Type, R genes. GG genotype of SNP rs454303072 was found to have wider rear udder, larger udder circumference, longer distance between fore-rear teats and left-right teats in Karan Fries cattle. Whereas, in Sahiwal cattle, AA genotype of this SNP was found to be associated with the higher and wider rear udder, larger udder circumference and wider udder. AA genotype of SNP rs382671389 was found to be associated with longer fore teat in Karan Fries cattle. The TT and CC genotype of SNP rs435289107 was associated with udder type traits in Karan Fries and Sahiwal cattle respectively. These results suggest that BTA 5 harbors genomic regions associated with udder traits in and x cattle.

摘要

奶牛的乳房结构不仅对展现外观特征至关重要，而且对提高产奶量和降低乳腺炎发病率也很重要。本研究测量了萨希瓦尔牛（）和卡里安弗莱牛（）的不同乳房类型特征，并研究了它们与维生素 D 受体和蛋白酪氨酸磷酸酶、受体型、R 基因中的单核苷酸多态性的关系。发现 SNP rs454303072 的 GG 基因型在卡里安弗莱牛中具有更宽的后乳房、更大的乳房周长、前-后乳头之间和左右乳头之间的距离更长。然而，在萨希瓦尔牛中，发现该 SNP 的 AA 基因型与更高和更宽的后乳房、更大的乳房周长和更宽的乳房有关。SNP rs382671389 的 AA 基因型与卡里安弗莱牛的前乳头较长有关。SNP rs435289107 的 TT 和 CC 基因型与卡里安弗莱牛和萨希瓦尔牛的乳房类型特征有关。这些结果表明，BTA5 含有与和牛的乳房特征相关的基因组区域。