Shen Chen, Fang Wentao
Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.
Zhongguo Fei Ai Za Zhi. 2022 Aug 20;25(8):593-600. doi: 10.3779/j.issn.1009-3419.2022.101.30.
The survival rate needs to be improved in early stage non-small cell lung cancer patients. The risk of recurrence is relatively high in invasive adenocarcinoma patients with a solid or micropapillary component, lymphovascular invasion or tumor spread through air spaces. Systemic treatment options including radical surgical resection should be explored for this population. Adjuvant chemotherapy is not recommended for patients in stage IA in current guidelines. This article is a review on the research progress of the above pathological high-risk factors and the role of adjuvant chemotherapy in patients with pathological high-risk factors in stage IA lung adenocarcinoma. .
早期非小细胞肺癌患者的生存率有待提高。在具有实性或微乳头成分、存在淋巴血管浸润或肿瘤通过气腔播散的浸润性腺癌患者中,复发风险相对较高。对于这部分人群,应探索包括根治性手术切除在内的全身治疗方案。目前的指南不建议ⅠA期患者接受辅助化疗。本文就上述病理高危因素的研究进展以及辅助化疗在ⅠA期肺腺癌病理高危因素患者中的作用进行综述。