产奥罗多克斯菌素细菌ATCC 21386的基因组序列。
Genome sequence of the aurodox-producing bacterium ATCC 21386.
作者信息
McHugh Rebecca E, Munnoch John T, Roe Andrew J, Hoskisson Paul A
机构信息
Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK.
Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, G12 8TA, UK.
出版信息
Access Microbiol. 2022 Aug 19;4(5):acmi000358. doi: 10.1099/acmi.0.000358. eCollection 2022 Aug.
We report the genome sequence of ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71%. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.
我们报告了ATCC 21386菌株的基因组序列，该菌株可产生抗菌和抗毒力聚酮化合物奥多霉素。使用多平台杂交方法对ATCC 21386的基因组进行了测序，结果显示其线性基因组大小约为10 Mbp，G+C含量为71%。基因组序列揭示了36个假定的生物合成基因簇（BGC），包括一个富含生物合成能力的271 Kbp的大片段。该基因组序列已存入DDBJ/EMBL/GenBank，登录号为PRJNA602141。
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