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Commentary: Revival of motor and sensory functions: Is this a catholicon or hollow promise for paraplegia?

作者信息

Agrawal Devendra K, Rai Vikrant

机构信息

Department of Translational Research, Western University of Health Sciences, Pomona, Calif.

出版信息

JTCVS Open. 2021 Jul 2;7:43-44. doi: 10.1016/j.xjon.2021.06.022. eCollection 2021 Sep.

DOI:10.1016/j.xjon.2021.06.022
PMID:36003689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9390623/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d96/9390623/e14e36ab646a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d96/9390623/f0c9b4165a13/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d96/9390623/e14e36ab646a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d96/9390623/f0c9b4165a13/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d96/9390623/e14e36ab646a/gr1.jpg

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Intravenous injection of adult human bone marrow mesenchymal stromal cells attenuates spinal cord ischemia/reperfusion injury in a murine aortic arch crossclamping model.在小鼠主动脉弓夹闭模型中，静脉注射成人骨髓间充质基质细胞可减轻脊髓缺血/再灌注损伤。
JTCVS Open. 2021 Jun 9;7:23-40. doi: 10.1016/j.xjon.2021.06.008. eCollection 2021 Sep.
2
Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis.源自骨髓间充质干细胞的外泌体通过抑制周细胞焦亡来保护受损脊髓。
Neural Regen Res. 2022 Jan;17(1):194-202. doi: 10.4103/1673-5374.314323.
3
Treatment of spinal cord injury with mesenchymal stem cells.
间充质干细胞治疗脊髓损伤
Cell Biosci. 2020 Sep 22;10:112. doi: 10.1186/s13578-020-00475-3. eCollection 2020.
4
Simulated microgravity-cultured mesenchymal stem cells improve recovery following spinal cord ischemia in rats.模拟微重力培养的间充质干细胞可改善大鼠脊髓缺血后的恢复情况。
Stem Cell Res. 2019 Dec;41:101601. doi: 10.1016/j.scr.2019.101601. Epub 2019 Oct 15.
5
Hypoxia preconditioning promotes bone marrow mesenchymal stem cells survival by inducing HIF-1α in injured neuronal cells derived exosomes culture system.缺氧预处理通过诱导损伤神经元细胞衍生的外体培养系统中的 HIF-1α 促进骨髓间充质干细胞的存活。
Cell Death Dis. 2019 Feb 12;10(2):134. doi: 10.1038/s41419-019-1410-y.
6
Roles of Mesenchymal Stem Cells in Spinal Cord Injury.间充质干细胞在脊髓损伤中的作用。
Stem Cells Int. 2017;2017:5251313. doi: 10.1155/2017/5251313. Epub 2017 May 28.
7
Hypoxic preconditioning increases the protective effect of bone marrow mesenchymal stem cells on spinal cord ischemia/reperfusion injury.缺氧预处理增强了骨髓间充质干细胞对脊髓缺血/再灌注损伤的保护作用。
Mol Med Rep. 2016 Mar;13(3):1953-60. doi: 10.3892/mmr.2016.4753. Epub 2016 Jan 11.
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Risk factors for spinal cord ischemia after endovascular repair of thoracoabdominal aortic aneurysms.胸腹主动脉瘤血管腔内修复术后脊髓缺血的危险因素。
J Vasc Surg. 2015 Jun;61(6):1408-16. doi: 10.1016/j.jvs.2015.01.044. Epub 2015 Mar 28.
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Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.骨髓间充质干细胞通过促进轴突生长和抗自噬来修复脊髓缺血/再灌注损伤。
Neural Regen Res. 2014 Sep 15;9(18):1665-71. doi: 10.4103/1673-5374.141801.
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