Interdisciplinary Center for Aquaculture Research, O'Higgins 1695, Concepción 4030000, Chile.
GreenCoLab-Associação Oceano Verde, Campus de Gambelas, Universidade do Algarve, 8005-139 Faro, Portugal.
Toxins (Basel). 2022 Aug 22;14(8):575. doi: 10.3390/toxins14080575.
Despite the invaluable role of anesthetics as a tool for ensuring animal welfare in stressful situations, there is currently a lack of anesthetic drugs that meet the requirements of intensive aquaculture. In response to the growing interest in anesthetic substances of natural origin, this study evaluated the physiological and health impact of an anesthetic based on an extract of the microalga on juvenile salmon () exposed for a period of 72 h. To simulate a condition closer to reality where fish are subjected to stimuli (e.g., transport), the animals were exposed to 50 mg L of algal extract and to physical stress. Functional, physiological, and histological parameters were evaluated in blood and tissues at different sampling periods (0, 24, and 72 h). There was no mortality and the induction and recovery times observed were within the established criteria for anesthetic efficacy. The anesthetic extract did not induce any side effects, such as stress or metabolic damage, indicating that this extract is a viable option for supporting fish welfare during deleterious events. This study provides information to support that the anesthetic extract tested, derived from , is a promising candidate drug for operations requiring sedation (e.g., Salmonid transport).
尽管麻醉剂在确保应激情况下动物福利方面发挥了重要作用，但目前仍缺乏符合集约化水产养殖要求的麻醉药物。针对人们对天然来源麻醉物质日益增长的兴趣，本研究评估了一种基于微藻提取物的麻醉剂对幼三文鱼 () 的生理和健康影响，这些三文鱼暴露于该麻醉剂中为期 72 小时。为了更接近现实情况模拟，即鱼类受到刺激（例如，运输），将动物暴露于 50mg/L 的藻类提取物和物理应激下。在不同的采样时间（0、24 和 72 小时）评估血液和组织中的功能、生理和组织学参数。没有观察到死亡，诱导和恢复时间符合麻醉效果的既定标准。麻醉提取物没有引起任何副作用，如应激或代谢损伤，这表明该提取物是在有害事件中支持鱼类福利的可行选择。本研究提供的信息支持了所测试的麻醉提取物，源自 ，是一种有前途的候选药物，可用于需要镇静的操作（例如，鲑鱼运输）。
