澳大利亚在新冠疫情期间对不同程度的限制措施下，怀孕意愿与女性心理困扰之间的关联。

Association between pregnancy intention and psychological distress among women exposed to different levels of restrictions during the COVID-19 pandemic in Australia.

机构信息

School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.

出版信息

PLoS One. 2022 Aug 25;17(8):e0273339. doi: 10.1371/journal.pone.0273339. eCollection 2022.

DOI:10.1371/journal.pone.0273339

PMID:36006931

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9409515/

Abstract

BACKGROUND

The COVID-19 pandemic has had a negative impact on the mental health of people globally. Significant concerns about health and access to services among women of reproductive age considering pregnancy may cause psychological distress, and in turn increase health risks during and after pregnancy for mothers and offspring.

OBJECTIVES

To examine the association between pregnancy intention and psychological distress during the COVID-19 pandemic in Australia, and explore if this association differed based on local viral transmission rates and corresponding levels of pandemic restrictions.

METHODS

A nationwide online survey was completed by 849 non-pregnant women aged 18-50 years between 15 October and 7 November 2020. Women were asked about their intention to become pregnant, and psychological distress was assessed using the Kessler Psychological Distress Scale (K10). Multivariable regression analysis examined associations between pregnancy intention and psychological distress. An interaction term was added to the model to examine differences in associations by level of viral transmission rates and lockdown restrictions which was determined based on postcode.

RESULTS

Pregnancy intention was not associated with experiencing (very) high psychological distress in the overall study population (odds ratio (OR) 1.42, 95% CI 0.94, 2.11). The interaction term (p = 0.09) suggested potential differences by level of restrictions and viral transmission rates. In stratified analysis among women living in a location with strict lockdown restrictions and high viral transmission rates leading up to and during the study, those planning to become pregnant were more likely to experience (very) high psychological distress (OR 3.39, 2.04, 5.65) compared with women not planning to become pregnant. Pregnancy intention was not associated with psychological distress among women exposed to lower levels of pandemic restrictions and viral transmission rates (OR 1.17, 0.74, 1.85).

CONCLUSIONS

Our findings highlight the need to identify and support women planning pregnancy during a public health crisis to mitigate potential short- and long-term intergenerational negative health outcomes associated with psychological distress.

摘要

背景

COVID-19 大流行对全球人口的心理健康产生了负面影响。考虑到怀孕的育龄妇女对健康和服务获取的重大担忧可能会导致心理困扰，进而增加母亲和后代在怀孕和怀孕后的健康风险。

目的

调查澳大利亚 COVID-19 大流行期间怀孕意愿与心理困扰之间的关联，并探讨这种关联是否因当地病毒传播率和相应的大流行限制水平而异。

方法

2020 年 10 月 15 日至 11 月 7 日期间，通过全国性在线调查对 849 名 18-50 岁的非孕妇进行了调查。询问妇女怀孕的意愿，并使用 Kessler 心理困扰量表（K10）评估心理困扰。多变量回归分析检查了怀孕意愿与心理困扰之间的关联。模型中添加了一个交互项，以检查基于邮政编码确定的病毒传播率和封锁限制水平差异对关联的影响。

结果

在整个研究人群中，怀孕意愿与经历（非常）高心理困扰无关（比值比 (OR) 1.42，95%置信区间 (CI) 0.94，2.11）。交互项（p=0.09）表明限制和病毒传播率水平存在差异。在对居住在限制严格且病毒传播率高的地点的女性进行分层分析中，在研究开始前和进行期间，与不打算怀孕的女性相比，计划怀孕的女性更有可能经历（非常）高的心理困扰（OR 3.39，2.04，5.65）。在接触到较低水平的大流行限制和病毒传播率的女性中，怀孕意愿与心理困扰无关（OR 1.17，0.74，1.85）。