IODINE-125 PLAQUE BRACHYTHERAPY FOR DIFFUSE CHOROIDAL HEMANGIOMA.
作者信息
Azarcon Corrina P, Qiu Richard L J, Sobol Ethan K, Hubbard G Baker, Craven Caroline M, Bergstrom Chris S, Wells Jill R
机构信息
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.
Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia; and.
出版信息
Retin Cases Brief Rep. 2024 Jan 1;18(1):51-58. doi: 10.1097/ICB.0000000000001334.
PURPOSE
To report 6 cases of diffuse choroidal hemangioma in children treated with iodine-125 plaque brachytherapy at a single tertiary care center.
METHODS
Retrospective case series.
RESULTS
Six pediatric patients diagnosed with diffuse choroidal hemangioma were included in the study. Preplaque visual acuity ranged from 20/150 to no light perception. All patients had extensive serous retinal detachment at presentation. An iodine-125 radioactive plaque was placed on the affected eye to administer a dose of 34.2-42.1 Gy to the tumor apex over a median of 4 days. Tumor regression and subretinal fluid resolution were observed in all eyes within 17 months of treatment. Visual acuity improved in two patients. Radiation-induced cataract and subretinal fibrosis were documented in one case, and one patient developed radiation retinopathy. No patients developed neovascular glaucoma within the follow-up time of 12-65 months.
CONCLUSION
Iodine-125 plaque radiotherapy is an effective option for diffuse choroidal hemangioma, although there is a risk for radiation-induced complications.
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