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综合癌症中心开设急性姑息治疗病房的临床效果。

Clinical Outcomes of Operating an Acute Palliative Care Unit at a Comprehensive Cancer Center.

机构信息

Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

Palliative Care Center, Yonsei Cancer Center, Yonsei University Health System, Seoul, Republic of Korea.

出版信息

JCO Oncol Pract. 2022 Oct;18(10):e1661-e1671. doi: 10.1200/OP.22.00163. Epub 2022 Aug 25.

Abstract

PURPOSE

Acute palliative care units (APCUs) are inpatient services in tertiary hospitals that provide intensive symptom management and assist in hospital discharge for transitions to hospice care. We aimed to analyze the clinical outcomes of operating an APCU at a comprehensive cancer center.

PATIENTS AND METHODS

We retrospectively reviewed the medical records of 1,440 consecutive patients admitted to the APCU and analyzed demographic and clinical information, discharge outcomes, symptom assessments using the Edmonton Symptom Assessment System, spiritual distress, and financial distress.

RESULTS

The median age of patients was 67.0 (range, 23-97) years, and 41% were female. The most common primary cancer types were lung (21.9%), hepatopancreatobiliary (14.1%), and colorectal cancers (12.9%). The median length of stay was 8.0 days (range, 1-60 days), and 31.0% of patients died in the APCU. Death in the APCU showed a significant decrease over time, and overall inpatient death in oncology wards did not increase after APCU opening. In total, 44.7% of patients were discharged to government-certified hospice centers. The proportion of patients discharged to certified hospice centers increased from 32.2% in 2015 to 62.4% in 2018. Among 715 patients with a follow-up evaluation 1 week after admission, Edmonton Symptom Assessment System symptom scores, spiritual distress, and financial distress showed statistically significant improvements compared with the baseline symptom scores ( < .001). This improvement was limited to patients who did not die in the APCU.

CONCLUSION

Patients with advanced cancer admitted to the APCU may experience significant improvements in distressing symptoms. The majority of patients requiring transition to hospice were successfully transferred to certified hospice centers. The percentage discharged alive improved over time.

摘要

目的

急性姑息治疗病房(APCUs)是三级医院的住院服务,提供强化症状管理,并协助患者从医院过渡到临终关怀。我们旨在分析综合癌症中心运营 APCU 的临床结果。

患者和方法

我们回顾性地审查了入住 APCU 的 1440 例连续患者的病历,并分析了人口统计学和临床信息、出院结果、使用埃德蒙顿症状评估系统进行的症状评估、精神困扰和财务困境。

结果

患者的中位年龄为 67.0 岁(范围 23-97 岁),41%为女性。最常见的原发性癌症类型是肺癌(21.9%)、肝胆胰癌(14.1%)和结直肠癌(12.9%)。中位住院时间为 8.0 天(范围 1-60 天),31.0%的患者在 APCU 中死亡。APCUs 中的死亡人数随时间呈显著下降趋势,APCUs 开放后肿瘤科住院患者的总住院死亡人数并未增加。共有 44.7%的患者出院到政府认证的临终关怀中心。出院到认证临终关怀中心的患者比例从 2015 年的 32.2%增加到 2018 年的 62.4%。在 715 例接受入院后 1 周随访评估的患者中,与基线症状评分相比,埃德蒙顿症状评估系统症状评分、精神困扰和财务困境均有显著改善(<0.001)。这种改善仅限于 APCU 中未死亡的患者。

结论

入住 APCU 的晚期癌症患者可能会经历明显的痛苦症状改善。大多数需要过渡到临终关怀的患者都成功转移到了认证的临终关怀中心。出院存活率随时间的推移而提高。

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