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与急性姑息治疗病房出院去向相关的因素。

Factors associated with discharge disposition on an acute palliative care unit.

机构信息

Division of Medical Oncology, Department of Medicine, University of Toronto, Toronto, Canada.

Department of Supportive Care, Princess Margaret Cancer Centre, University Health Network, 610 University Ave., 16-712, Toronto, Ontario, M5G 2M9, Canada.

出版信息

Support Care Cancer. 2018 Nov;26(11):3951-3958. doi: 10.1007/s00520-018-4274-2. Epub 2018 May 30.

Abstract

PURPOSE

Acute palliative care units (APCUs) admit patients with cancer for symptom control, transition to community palliative care units or hospice (CPCU/H), or end-of-life care. Prognostication early in the course of admission is crucial for decision-making. We retrospectively evaluated factors associated with patients' discharge disposition on an APCU in a cancer center.

METHODS

We evaluated demographic, administrative, and clinical data for all patients admitted to the APCU in 2015. Clinical data included cancer diagnosis, delirium screening, and Edmonton Symptom Assessment System (ESAS) symptoms. An ESAS sub-score composed of fatigue, drowsiness, shortness of breath, and appetite (FDSA) was also investigated. Factors associated with patients' discharge disposition (home, CPCU/H, died on APCU) were identified using three-level multinomial logistic regression.

RESULTS

Among 280 patients, the median age was 65.5 and median length of stay was 10 days; 155 (55.4%) were admitted for symptom control, 65 (23.2%) for transition to CPCU/H, and 60 (21.4%) for terminal care. Discharge dispositions were as follows: 156 (55.7%) died, 63 (22.5%) returned home, and 61 (21.8%) were transferred to CPCU/H. On multivariable analysis, patients who died were less likely to be older (OR 0.97, p = 0.01), or to be admitted for symptom control (OR 0.06, p < 0.0001), and more likely to have a higher FDSA score 21-40 (OR 3.02, p = 0.004). Patients discharged to CPCU/H were less likely to have been admitted for symptom control (OR 0.06, p < 0.0001).

CONCLUSION

Age, reason for admission, and the FDSA symptom cluster on admission are variables that can inform clinicians about probable discharge disposition on an APCU.

摘要

目的

急性姑息治疗病房(APCUs)收治癌症患者,以控制症状、过渡到社区姑息治疗病房或临终关怀(CPCU/H)或临终关怀。在入院早期进行预后评估对决策至关重要。我们回顾性评估了癌症中心 APCU 入院患者出院去向的相关因素。

方法

我们评估了 2015 年入住 APCU 的所有患者的人口统计学、行政和临床数据。临床数据包括癌症诊断、谵妄筛查和埃德蒙顿症状评估系统(ESAS)症状。还研究了由疲劳、嗜睡、呼吸急促和食欲组成的 ESAS 亚量表(FDSA)。使用三级多项逻辑回归识别与患者出院去向(家庭、CPCU/H、APCUs 死亡)相关的因素。

结果

在 280 名患者中,中位年龄为 65.5 岁,中位住院时间为 10 天;155 名(55.4%)因症状控制入院,65 名(23.2%)因过渡到 CPCU/H 入院,60 名(21.4%)因终末期护理入院。出院情况如下:156 人(55.7%)死亡,63 人(22.5%)返回家中,61 人(21.8%)转至 CPCU/H。多变量分析显示,死亡患者年龄较小(OR 0.97,p=0.01),或因症状控制入院(OR 0.06,p<0.0001)的可能性较小,FDSA 评分较高(21-40 分)(OR 3.02,p=0.004)的可能性更大。转至 CPCU/H 的患者不太可能因症状控制而入院(OR 0.06,p<0.0001)。

结论

年龄、入院原因和入院时的 FDSA 症状群是可以告知临床医生 APCU 可能出院去向的变量。

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