Blair Kyle, Czyz Craig, Smithers Joshua, Yassall Anthony
Department of Ophthalmology, OhioHealth Doctors Hospital, Columbus, Ohio.
Ohio University Heritage College of Osteopathic Medicine, Dublin, Ohio .
Retin Cases Brief Rep. 2024 Jan 1;18(1):59-61. doi: 10.1097/ICB.0000000000001327.
BACKGROUND/PURPOSE: Branch retinal artery occlusions (BRAO) are primarily associated with the aging population and are rare in young adults. The etiology of BRAO includes embolic or nonembolic sources. Lisdexamfetamine has been associated with vasospastic ischemic events in multiple areas of the body. However, there are currently no reported cases of BRAO associated with lisdexamfetamine use. Here, we present a case that suggests a correlation between lisdexamfetamine use and a nonembolic BRAO in a young adult man.
METHODS/RESULTS: A 32-year-old man presented with sudden left eye blurred vision 17 days after beginning lisdexamfetamine. Fundus examination confirmed the BRAO diagnosis. Following evaluation by a retina specialist, vasospasm was considered the most likely cause for the BRAO. Other possible etiologies were unlikely due to diagnostic testing.
The temporal association between lisdexamfetamine and BRAO symptom onset suggests vasospastic occlusion. Lisdexamfetamine-associated adverse events should be considered as a possible etiology for BRAO.
背景/目的：视网膜分支动脉阻塞（BRAO）主要与老年人群相关，在年轻人中较为罕见。BRAO的病因包括栓塞性或非栓塞性来源。赖氨酸安非他命已与身体多个部位的血管痉挛性缺血事件相关。然而，目前尚无与使用赖氨酸安非他命相关的BRAO病例报告。在此，我们报告一例提示年轻男性使用赖氨酸安非他命与非栓塞性BRAO之间存在关联的病例。
方法/结果：一名32岁男性在开始使用赖氨酸安非他命17天后出现左眼突发视力模糊。眼底检查确诊为BRAO。经视网膜专科医生评估，血管痉挛被认为是BRAO最可能的病因。由于诊断测试，其他可能的病因不太可能。
赖氨酸安非他命与BRAO症状发作之间的时间关联提示血管痉挛性阻塞。应考虑将与赖氨酸安非他命相关的不良事件作为BRAO的一种可能病因。
