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新生儿卡介苗:是时候改变了。

Neonatal BCG: a time for change.

机构信息

Neonatology, University Hospitals of Leicester NHS Trust, Leicester, UK

Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton, UK.

出版信息

Arch Dis Child Educ Pract Ed. 2024 Jan 23;109(1):19-24. doi: 10.1136/archdischild-2021-323239.

DOI:10.1136/archdischild-2021-323239
PMID:36008111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10850640/
Abstract

The BCG vaccination programme in the UK is risk based and has usually been given to eligible babies soon after birth. On advice from the Joint Committee on Vaccination and Immunisation, NHS England and Improvement recently revised the timing of this vaccination to 28 days after birth or soon thereafter. In this article, we highlight the change in timing of vaccination, the rationale and barriers to BCG uptake that this change may pose.

摘要

英国的卡介苗(BCG)接种计划是基于风险的,通常在婴儿出生后不久就会给符合条件的婴儿接种。根据疫苗接种和免疫联合委员会、英格兰国民保健制度(NHS England)和改进组织的建议,最近修改了该疫苗的接种时间,改为出生后 28 天或之后尽快接种。在本文中,我们重点介绍了接种时间的变化、这种变化可能带来的 BCG 接种率提高的理由和障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3597/10850640/cd0c3978304e/edpract-2021-323239f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3597/10850640/cd0c3978304e/edpract-2021-323239f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3597/10850640/cd0c3978304e/edpract-2021-323239f01.jpg

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1
Neonatal BCG: a time for change.新生儿卡介苗:是时候改变了。
Arch Dis Child Educ Pract Ed. 2024 Jan 23;109(1):19-24. doi: 10.1136/archdischild-2021-323239.
2
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引用本文的文献

1
Parents' perspectives of the new neonatal BCG vaccination pathway in England: a qualitative study.英格兰父母对新生儿卡介苗接种新途径的看法:一项定性研究
BMC Public Health. 2025 Aug 18;25(1):2821. doi: 10.1186/s12889-025-23859-x.
2
A new neonatal BCG vaccination pathway in England: a mixed methods evaluation of its implementation.英格兰一种新的新生儿卡介苗接种途径:对其实施情况的混合方法评估
BMC Public Health. 2024 Apr 26;24(1):1175. doi: 10.1186/s12889-024-18586-8.

本文引用的文献

1
Universal Newborn Screening for Severe Combined Immunodeficiency (SCID).严重联合免疫缺陷(SCID)的新生儿普遍筛查
Front Pediatr. 2019 Sep 18;7:373. doi: 10.3389/fped.2019.00373. eCollection 2019.
2
What Have We Learnt about BCG Vaccination in the Last 20 Years?在过去20年里,我们对卡介苗接种有了哪些了解?
Front Immunol. 2017 Sep 13;8:1134. doi: 10.3389/fimmu.2017.01134. eCollection 2017.
3
Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis.卡介苗接种对儿童结核分枝杆菌感染的影响:系统评价与荟萃分析
BMJ. 2014 Aug 5;349:g4643. doi: 10.1136/bmj.g4643.
4
Protection by BCG vaccine against tuberculosis: a systematic review of randomized controlled trials.BCG 疫苗预防结核病的效果:随机对照试验的系统评价。
Clin Infect Dis. 2014 Feb;58(4):470-80. doi: 10.1093/cid/cit790. Epub 2013 Dec 13.
5
Fifteen-minute consultation: Bacillus Calmette-Guérin abscess and lymphadenitis.15分钟会诊:卡介苗脓肿及淋巴结炎
Arch Dis Child Educ Pract Ed. 2014 Jun;99(3):87-9. doi: 10.1136/archdischild-2013-304457. Epub 2013 Nov 8.
6
Tuberculosis contact investigation in low prevalence countries: a European consensus.低发病国家的结核病接触者调查:欧洲共识。
Eur Respir J. 2010 Oct;36(4):925-49. doi: 10.1183/09031936.00201609.
7
Influence of BCG vaccine strain on the immune response and protection against tuberculosis.卡介苗菌株对免疫反应及结核病防护的影响
FEMS Microbiol Rev. 2008 Aug;32(5):821-41. doi: 10.1111/j.1574-6976.2008.00118.x. Epub 2008 Jul 9.
8
Effect of BCG vaccination on childhood tuberculous meningitis and miliary tuberculosis worldwide: a meta-analysis and assessment of cost-effectiveness.卡介苗接种对全球儿童结核性脑膜炎和粟粒性肺结核的影响:一项荟萃分析及成本效益评估
Lancet. 2006 Apr 8;367(9517):1173-80. doi: 10.1016/S0140-6736(06)68507-3.
9
Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature.卡介苗预防结核病的疗效。已发表文献的荟萃分析。
JAMA. 1994 Mar 2;271(9):698-702.
10
Protective effect of BCG against tuberculous meningitis and miliary tuberculosis: a meta-analysis.卡介苗对结核性脑膜炎和粟粒性肺结核的保护作用:一项荟萃分析。
Int J Epidemiol. 1993 Dec;22(6):1154-8. doi: 10.1093/ije/22.6.1154.