Pan Szu-Ying, Huang Chi-Ping, Chen Wen-Chi
Department of Urology, China Medical University Hospital, Taichung 404332, Taiwan.
School of Medicine, College of Chinese Medicine, China Medical University, Taichung 404332, Taiwan.
Diagnostics (Basel). 2022 Aug 11;12(8):1940. doi: 10.3390/diagnostics12081940.
The incidence of secondary primary malignancy (SPM) has been reported to range from 1.33% to 5.8%, according to the location of the primary cancer and the follow-up duration. The highest occurrence rate of SPM, of 36.6% within 6 months, has been reported in lung cancer. Genitourinary malignancies were reported to be the third-most-common SPM in several reports. However, the incidence of genitourinary malignancy as the first primary cancer associated with SPM has not been reported. Several risk factors are related to the occurrence of SPM, including viral infection chemotherapy, radiation, genetics, smoking, betel quid chewing, and environmental factors. An early survey for SPM is indicated in first primary malignancy patients with these associated factors. In this study, we summarize several risk factors related to the occurrence of SPMs and preventive tests, which may help in their early detection and, consequently, better survival.
据报道，根据原发性癌症的位置和随访时间，继发性原发性恶性肿瘤（SPM）的发生率在1.33%至5.8%之间。肺癌的SPM发生率最高，在6个月内为36.6%。在几份报告中，泌尿生殖系统恶性肿瘤被报道为第三常见的SPM。然而，尚未有关于泌尿生殖系统恶性肿瘤作为与SPM相关的首个原发性癌症的发生率的报道。几种危险因素与SPM的发生有关，包括病毒感染、化疗、放疗、遗传、吸烟、嚼槟榔和环境因素。对于有这些相关因素的首个原发性恶性肿瘤患者，建议进行SPM的早期筛查。在本研究中，我们总结了与SPM发生相关的几种危险因素和预防性检查，这可能有助于早期发现SPM，从而提高生存率。
