• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

特刊：肿瘤诊断与治疗中的下一代测序II

Special Issue: Next-Generation Sequencing in Tumor Diagnosis and Treatment II.

作者信息

Malapelle Umberto, Fassan Matteo, de Biase Dario

机构信息

Department of Public Health, University of Naples Federico II, 80138 Naples, Italy.

Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, 35122 Padua, Italy.

出版信息

Diagnostics (Basel). 2022 Aug 20;12(8):2017. doi: 10.3390/diagnostics12082017.

DOI:10.3390/diagnostics12082017
PMID:36010367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9407571/
Abstract

Next-generation sequencing (NGS) allows for the sequencing of multiple genes at a very high depth of coverage [...].

摘要

下一代测序（NGS）能够在非常高的覆盖深度下对多个基因进行测序[……]。

相似文献

1
Special Issue: Next-Generation Sequencing in Tumor Diagnosis and Treatment II.特刊：肿瘤诊断与治疗中的下一代测序II
Diagnostics (Basel). 2022 Aug 20;12(8):2017. doi: 10.3390/diagnostics12082017.
2
Next-Generation Sequencing in Tumor Diagnosis and Treatment.肿瘤诊断与治疗中的下一代测序技术
Diagnostics (Basel). 2020 Nov 17;10(11):962. doi: 10.3390/diagnostics10110962.
3
Standardization of Sequencing Coverage Depth in NGS: Recommendation for Detection of Clonal and Subclonal Mutations in Cancer Diagnostics.二代测序中测序覆盖深度的标准化：癌症诊断中克隆性和亚克隆性突变检测的建议
Front Oncol. 2019 Sep 4;9:851. doi: 10.3389/fonc.2019.00851. eCollection 2019.
4
Molecular Diagnostic of Solid Tumor Using a Next Generation Sequencing Custom-Designed Multi-Gene Panel.使用二代测序定制多基因panel对实体瘤进行分子诊断
Diagnostics (Basel). 2020 Apr 23;10(4):250. doi: 10.3390/diagnostics10040250.
5
Next-generation sequencing in the diagnosis of non-cirrhotic splanchnic vein thrombosis.下一代测序在非肝硬化性内脏静脉血栓形成诊断中的应用。
J Hepatol. 2021 Jan;74(1):89-95. doi: 10.1016/j.jhep.2020.06.045. Epub 2020 Jul 15.
6
Next-generation sequencing of custom amplicons to improve coverage of HaloPlex multigene panels.定制扩增子的新一代测序以提高HaloPlex多基因检测板的覆盖范围。
Biotechniques. 2014 Oct 1;57(4):204-7. doi: 10.2144/000114217. eCollection 2014 Oct.
7
Primer ID Validates Template Sampling Depth and Greatly Reduces the Error Rate of Next-Generation Sequencing of HIV-1 Genomic RNA Populations.引物ID验证模板采样深度并大幅降低HIV-1基因组RNA群体下一代测序的错误率。
J Virol. 2015 Aug;89(16):8540-55. doi: 10.1128/JVI.00522-15. Epub 2015 Jun 3.
8
Next generation sequencing technology: Advances and applications.下一代测序技术：进展与应用
Biochim Biophys Acta. 2014 Oct;1842(10):1932-1941. doi: 10.1016/j.bbadis.2014.06.015. Epub 2014 Jul 1.
9
Targeted NGS: A Cost-Effective Approach to Molecular Diagnosis of PIDs.靶向二代测序：一种用于原发性免疫缺陷病分子诊断的经济高效方法。
Front Immunol. 2014 Nov 3;5:531. doi: 10.3389/fimmu.2014.00531. eCollection 2014.
10
A comparative study of k-spectrum-based error correction methods for next-generation sequencing data analysis.基于k谱的下一代测序数据分析纠错方法的比较研究。
Hum Genomics. 2016 Jul 25;10 Suppl 2(Suppl 2):20. doi: 10.1186/s40246-016-0068-0.

本文引用的文献

1
FFPE-Based NGS Approaches into Clinical Practice: The Limits of Glory from a Pathologist Viewpoint.基于福尔马林固定石蜡包埋组织的二代测序方法应用于临床实践：从病理学家视角看辉煌背后的局限
J Pers Med. 2022 May 5;12(5):750. doi: 10.3390/jpm12050750.
2
Comprehensive Development and Implementation of Good Laboratory Practice for NGS Based Targeted Panel on Solid Tumor FFPE Tissues in Diagnostics.基于二代测序的实体瘤FFPE组织靶向测序诊断实验室规范的全面开发与实施
Diagnostics (Basel). 2022 May 23;12(5):1291. doi: 10.3390/diagnostics12051291.
3
Utility of Next-Generation Sequencing in the Reconstruction of Clonal Architecture in a Patient with an Mutated Advanced Non-Small Cell Lung Cancer: A Case Report.二代测序在一名晚期非小细胞肺癌突变患者克隆结构重建中的应用：病例报告
Diagnostics (Basel). 2022 May 19;12(5):1266. doi: 10.3390/diagnostics12051266.
4
Molecular Characterization of Pancreatic Ductal Adenocarcinoma Using a Next-Generation Sequencing Custom-Designed Multigene Panel.使用定制设计的二代测序多基因检测板对胰腺导管腺癌进行分子特征分析
Diagnostics (Basel). 2022 Apr 23;12(5):1058. doi: 10.3390/diagnostics12051058.
5
Multiple Genetic Alterations as Resistance Mechanism during Second-Line Lorlatinib for Advanced ALK-Rearranged Lung Adenocarcinoma: A Case Report.多基因改变作为晚期ALK重排肺腺癌二线劳拉替尼治疗期间的耐药机制：一例报告
Diagnostics (Basel). 2022 Mar 11;12(3):682. doi: 10.3390/diagnostics12030682.
6
Development and Validation of a Targeted 'Liquid' NGS Panel for Treatment Customization in Patients with Metastatic Colorectal Cancer.用于转移性结直肠癌患者治疗定制的靶向“液体”NGS检测板的开发与验证
Diagnostics (Basel). 2021 Dec 16;11(12):2375. doi: 10.3390/diagnostics11122375.
7
Next generation diagnostic algorithm in non-small cell lung cancer predictive molecular pathology: The KWAY Italian multicenter cost evaluation study.非小细胞肺癌预测性分子病理学中的下一代诊断算法：KWAY 意大利多中心成本评估研究。
Crit Rev Oncol Hematol. 2022 Jan;169:103525. doi: 10.1016/j.critrevonc.2021.103525. Epub 2021 Nov 20.
8
Implementation of Next Generation Sequencing-Based Liquid Biopsy for Clinical Molecular Diagnostics in Non-Small Cell Lung Cancer (NSCLC) Patients.基于下一代测序的液体活检在非小细胞肺癌（NSCLC）患者临床分子诊断中的应用
Diagnostics (Basel). 2021 Aug 13;11(8):1468. doi: 10.3390/diagnostics11081468.
9
Feasibility of Testing of Formalin-Fixed and Paraffin-Embedded Pancreatic Tumor Samples: A Consecutive Clinical Series.福尔马林固定石蜡包埋胰腺肿瘤样本检测的可行性：一项连续临床系列研究
Diagnostics (Basel). 2021 Jun 7;11(6):1046. doi: 10.3390/diagnostics11061046.
10
Liquid biopsy enters the clinic - implementation issues and future challenges.液体活检进入临床——实施问题与未来挑战。
Nat Rev Clin Oncol. 2021 May;18(5):297-312. doi: 10.1038/s41571-020-00457-x. Epub 2021 Jan 20.