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糖尿病治疗与精神疾病:呼吁在马来西亚欠发达半农村地区建立综合性医疗保健系统。

Diabetes Treatment and Mental Illness: A Call for an Integrated Health Care System in Underserved Semi-Rural Malaysia.

机构信息

South East Asia Community Observatory (SEACO) & Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya 47500, Malaysia.

Department of Psychosomatic Medicine and Psychotherapy, University of Giessen and Marburg, 35392 Giessen, Germany.

出版信息

Int J Environ Res Public Health. 2022 Aug 14;19(16):10015. doi: 10.3390/ijerph191610015.

DOI:10.3390/ijerph191610015
PMID:36011650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9408510/
Abstract

Diabetes mellitus (DM) management imposes a tremendous psychological burden on patients. The study investigates the association between DM treatment with blood glucose (BG) control and common mental health conditions. A cross-sectional study was conducted among 1821 individuals with DM in a community-based survey conducted in 2013. Information on respondents’ sociodemographic, mental health, DM treatment, and BG levels was collected. Multinomial logistic regression was employed to examine the association of diabetes treatment with controlled BG levels (<11.1 mmol/L) (42.5%, n = 774) or uncontrolled BG levels (34.3%, n = 625) compared with those not undergoing treatment (23.2%, n = 422) on depression anxiety, and stress. Having DM treatment and controlled BG was associated with high depressive symptoms (Relative Risk Ratio, RRR: 2.42; 95% CI 1.33−4.41) and high anxiety symptoms (1.66; 1.08−2.56) but not with perceived stress. However, treated DM with uncontrolled BG was associated with anxiety (high: 1.64; 1.05−2.56; low: 2.59; 1.10−6.09) but not depression or perceived stress. Our results suggest that being treated for DM, regardless of glucose control status, was associated with anxiety symptoms, whereas being treated with controlled BG was associated with high depressive symptoms. This situation highlights the need for integrative, multidisciplinary care for DM patients with mental health comorbidities.

摘要

糖尿病(DM)管理给患者带来了巨大的心理负担。本研究调查了 DM 治疗与血糖(BG)控制和常见心理健康状况之间的关系。在 2013 年进行的一项基于社区的调查中,对 1821 名 DM 患者进行了横断面研究。收集了受访者的社会人口统计学、心理健康、DM 治疗和 BG 水平的信息。采用多变量逻辑回归分析了与未接受治疗者(23.2%,n=422)相比,DM 治疗与控制 BG 水平(<11.1mmol/L)(42.5%,n=774)或未控制 BG 水平(34.3%,n=625)的相关性,以评估与抑郁、焦虑和压力相关的情况。DM 治疗和控制 BG 与高抑郁症状(相对风险比,RRR:2.42;95%CI 1.33−4.41)和高焦虑症状(1.66;1.08−2.56)相关,但与感知压力无关。然而,未经控制的 BG 治疗的 DM 与焦虑(高:1.64;1.05−2.56;低:2.59;1.10−6.09)有关,但与抑郁或感知压力无关。我们的结果表明,无论血糖控制状况如何,接受 DM 治疗与焦虑症状有关,而控制 BG 的治疗与高抑郁症状有关。这种情况突出表明需要对患有精神共病的 DM 患者进行综合的多学科护理。

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PLoS One. 2022 Jan 18;17(1):e0262714. doi: 10.1371/journal.pone.0262714. eCollection 2022.
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Chronic Inflammation Mediates the Association between Cortisol and Hyperglycemia: Findings from the Cross-Sectional Population-Based KORA Age Study.慢性炎症介导皮质醇与高血糖之间的关联:基于人群的横断面KORA年龄研究结果
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BMJ Open. 2021 Jun 30;11(6):e043923. doi: 10.1136/bmjopen-2020-043923.
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Prevalence, awareness, treatment, and control of diabetes mellitus by depressive symptom severity: a cross-sectional analysis of NHANES 2011-2016.2011-2016 年 NHANES 横断面分析:按抑郁症状严重程度分层的糖尿病患病率、知晓率、治疗率和控制率。
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