Cornea Amalia, Simu Mihaela, Rosca Elena Cecilia
Department of Neurology, Victor Babes University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.
Department of Neurology, Clinical Emergency County Hospital Timisoara, Boulevard Iosif Bulbuca No. 10, 300736 Timisoara, Romania.
J Clin Med. 2022 Aug 10;11(16):4679. doi: 10.3390/jcm11164679.
Subarachnoid hemorrhage (SAH) is a severe condition with high mortality and extensive long-term morbidity. Although research has focused mainly on physical signs and disability for decades, in recent years, it has been increasingly recognized that cognitive and psychological impairments may be present in many patients with SAH, negatively impacting their quality of life. We performed a systematic review aiming to provide a comprehensive report on the diagnostic accuracy of the Montreal Cognitive Assessment (MoCA) test for evaluating the presence of cognitive impairment in patients with SAH. Using appropriate search terms, we searched five databases (PubMed, Scopus, PsychINFO, Web of Sciences, and Latin American and Caribbean Health Sciences Literature) up to January 2022. Two cross-sectional studies investigated the accuracy of MoCA in SAH patients in the subacute and chronic phase. We appraised the quality of the included studies using the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) criteria. The MoCA test provides information about general cognitive functioning disturbances. However, a lower threshold than the original cutoff might be needed as it improves diagnostic accuracy, lowering the false positive rates. Further research is necessary for an evidence-based decision to use the MoCA in SAH patients.
蛛网膜下腔出血(SAH)是一种严重疾病,死亡率高且长期存在广泛的发病情况。尽管几十年来研究主要集中在体征和残疾方面,但近年来,人们越来越认识到许多SAH患者可能存在认知和心理障碍,对他们的生活质量产生负面影响。我们进行了一项系统综述,旨在全面报告蒙特利尔认知评估(MoCA)测试在评估SAH患者认知障碍存在情况时的诊断准确性。我们使用适当的检索词,检索了截至2022年1月的五个数据库(PubMed、Scopus、PsychINFO、科学网和拉丁美洲及加勒比健康科学文献数据库)。两项横断面研究调查了MoCA在亚急性和慢性期SAH患者中的准确性。我们使用诊断准确性研究质量评估2(QUADAS - 2)标准评估纳入研究的质量。MoCA测试提供有关一般认知功能障碍的信息。然而,可能需要比原始临界值更低的阈值,因为这样可以提高诊断准确性,降低假阳性率。对于基于证据决定在SAH患者中使用MoCA,还需要进一步研究。