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运动对心血管疾病氧化还原平衡的影响

The Impact of Exercise on Redox Equilibrium in Cardiovascular Diseases.

作者信息

Sutkowy Paweł, Wróblewska Joanna, Wróblewski Marcin, Nuszkiewicz Jarosław, Modrzejewska Martyna, Woźniak Alina

机构信息

Department of Medical Biology and Biochemistry, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-092 Bydgoszcz, Poland.

出版信息

J Clin Med. 2022 Aug 18;11(16):4833. doi: 10.3390/jcm11164833.

Abstract

Cardiovascular diseases constitute the most important public health problem in the world. They are characterized by inflammation and oxidative stress in the heart and blood. Physical activity is recognized as one of the best ways to prevent these diseases, and it has already been applied in treatment. Physical exercise, both aerobic and anaerobic and single and multiple, is linked to the oxidant-antioxidant imbalance; however, this leads to positive adaptive changes in, among others, the increase in antioxidant capacity. The goal of the paper was to discuss the issue of redox equilibrium in the human organism in the course of cardiovascular diseases to systemize updated knowledge in the context of exercise impacts on the organism. Antioxidant supplementation is also an important issue since antioxidant supplements still have great potential regarding their use as drugs in these diseases.

摘要

心血管疾病是世界上最重要的公共卫生问题。其特征是心脏和血液中的炎症和氧化应激。体育活动被认为是预防这些疾病的最佳方法之一,并且已经应用于治疗。体育锻炼,包括有氧和无氧、单一和多种形式,都与氧化-抗氧化失衡有关;然而,这会导致机体产生积极的适应性变化,其中包括抗氧化能力的增强。本文的目的是讨论心血管疾病过程中人体氧化还原平衡的问题,以便在运动对机体影响的背景下系统整理最新知识。抗氧化剂补充也是一个重要问题,因为抗氧化剂补充剂在作为这些疾病的药物使用方面仍有很大潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77b6/9410476/2c4729df984f/jcm-11-04833-g001.jpg

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