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2-甲基丙烯酰氧乙基磷酰胆碱聚合物材料对正畸摩擦力及口腔细菌黏附的影响

The Influence of 2-Methacryloyloxyethyl Phosphorylcholine Polymer Materials on Orthodontic Friction and Attachment of Oral Bacteria.

作者信息

Kunimatsu Ryo, Tsuka Yuji, Nakajima Kengo, Sumi Keisuke, Yoshimi Yuki, Kado Isamu, Inada Ayako, Kiritoshi Yoshihiro, Tanimoto Kotaro

机构信息

Department of Orthodontics and Craniofacial Development Biology, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.

Intelligent Surfaces, Inc., Kashiwa 277-0882, Japan.

出版信息

Materials (Basel). 2022 Aug 21;15(16):5770. doi: 10.3390/ma15165770.

DOI:10.3390/ma15165770
PMID:36013906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9415717/
Abstract

There is no clinical evidence of the usage of 2-methacryloyloxyethyl phosphorylcholine (MPC) polymers in dental practice. We performed in vitro studies to determine whether the application of an MPC coating to stainless steel orthodontic wires confers low-friction and antimicrobial properties to these wires. The friction test on MPC-coated wires was performed using a precision universal/tensile tester. MPC polymer was coated on a 50 × 50 mm stainless steel plate, and samples were assessed using an antimicrobial activity test. To verify the effect of MPC polymer-treated wires on experimental tooth movement models in vitro, examinations were performed on typodonts to determine the improvement in tooth movement efficiency. The polymer treatment wire groups demonstrated significantly enhanced tooth movement compared with the untreated wire groups, at both 50 g and 100 g traction forces. The results indicated that MPC coating inhibited the attachment of oral bacteria, such as , on a stainless steel plate. Additionally, the coating seemed to improve the efficiency of tooth movement by reducing the occurrence of friction. The application of an MPC coating onto stainless steel wires, which are used as orthodontic materials, may reduce static friction and bacterial adherence to the oral cavity and improve tooth movement.

摘要

在牙科实践中,尚无使用2-甲基丙烯酰氧基乙基磷酰胆碱(MPC)聚合物的临床证据。我们进行了体外研究,以确定在不锈钢正畸丝上涂覆MPC涂层是否能赋予这些丝低摩擦和抗菌性能。使用精密万能/拉伸试验机对涂覆MPC的丝进行摩擦测试。将MPC聚合物涂覆在50×50mm的不锈钢板上,并使用抗菌活性测试对样品进行评估。为了在体外验证经MPC聚合物处理的丝对实验性牙齿移动模型的影响,在牙模型上进行检查以确定牙齿移动效率的提高。在50g和100g的牵引力下,聚合物处理丝组与未处理丝组相比,牙齿移动明显增强。结果表明,MPC涂层抑制了口腔细菌如 在不锈钢板上的附着。此外,该涂层似乎通过减少摩擦的发生来提高牙齿移动效率。在用作正畸材料的不锈钢丝上涂覆MPC涂层,可能会减少静摩擦和细菌在口腔中的黏附,并改善牙齿移动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/f5d92d995ca6/materials-15-05770-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/ce2fc53fe57d/materials-15-05770-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/428e2392378e/materials-15-05770-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/a9f2bc3d93ee/materials-15-05770-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/440002873353/materials-15-05770-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/f5d92d995ca6/materials-15-05770-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/ce2fc53fe57d/materials-15-05770-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/428e2392378e/materials-15-05770-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/a9f2bc3d93ee/materials-15-05770-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/440002873353/materials-15-05770-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/9415717/f5d92d995ca6/materials-15-05770-g005.jpg

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