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胫骨远端骨折相关感染的联合矫形外科治疗方法

Combined Orthoplastic Approach in Fracture-Related Infections of the Distal Tibia.

作者信息

Sambri Andrea, Pignatti Marco, Tedeschi Sara, Lozano Miralles Maria Elisa, Giannini Claudio, Fiore Michele, Filippini Matteo, Cipriani Riccardo, Viale Pierluigi, De Paolis Massimiliano

机构信息

Orthopaedics Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.

Plastic Surgery Unit, IRCCS AOU di Bologna, 40138 Bologna, Italy.

出版信息

Microorganisms. 2022 Aug 12;10(8):1640. doi: 10.3390/microorganisms10081640.

Abstract

This series reports on the treatment of distal tibia (DT) fracture-related infections (FRI) with a combined orthoplastic approach. Thirteen patients were included. In eight patients with extensive bone involvement and in those with a non-healed fracture, the DT was resected ("staged approach"). In five cases, the DT was preserved ("single-stage approach"). A wide debridement was performed, and the cavity was filled with antibiotic-loaded PerOssal beads. All patients had a soft-tissue defect covered by a free vascularized flap (anterolateral thigh perforator flap in eight cases, latissimus dorsi flap in five). At the final follow-up (mean 25 months, range, 13-37), no infection recurrence was observed. In one patient, the persistence of infection was observed, and the patient underwent a repeated debridement. In two cases, a voluminous hematoma was observed. However, none of these complications impacted the final outcome. The successful treatment of FRI depends on proper debridement and obliteration of dead spaces with a flap. Therefore, when dealing with DT FRI, debridement of infected bone and soft tissues must be as radical as required, with no fear of the need for massive reconstructions.

摘要

本系列报道了采用整形外科联合方法治疗胫骨远端(DT)骨折相关感染(FRI)的情况。共纳入13例患者。8例广泛骨质受累患者及骨折未愈合患者,行DT切除术(“分期手术”)。5例患者保留DT(“一期手术”)。进行广泛清创,并用载抗生素的PerOssal珠填充骨腔。所有患者均有软组织缺损,采用游离带血管皮瓣覆盖(8例采用股前外侧穿支皮瓣,5例采用背阔肌皮瓣)。末次随访时(平均25个月,范围13 - 37个月),未观察到感染复发。1例患者观察到感染持续存在,接受了再次清创。2例出现大量血肿。然而,这些并发症均未影响最终结局。FRI的成功治疗取决于适当的清创和用皮瓣消除死腔。因此,处理DT FRI时,对感染骨和软组织的清创必须达到所需的彻底程度,不必担心需要进行大规模重建。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5334/9414956/83cc80241fef/microorganisms-10-01640-g001.jpg

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