Zheng Yujiao, Cheng Jinbo, Gu Chengjuan, Xiao Mingzhong, Shao Zuoyu, Zhao Linhua, Tong Xiaolin
College of Traditional Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China.
Xinqiao Hospital, Army Medical University, Chongqing, China.
Front Med (Lausanne). 2022 Aug 9;9:860681. doi: 10.3389/fmed.2022.860681. eCollection 2022.
Coronavirus disease 2019 (COVID-19) has rapidly spread around the world since December 2019, becoming a global pandemic. Atypical cases of COVID-19, manifesting as prolonged positive SARS-CoV-2 test results during the convalescence period, have been encountered. These cases increase the difficulty of COVID-19 prevention and treatment. Here, we report five cases of COVID-19 patients who demonstrated prolonged positive SARS-CoV-2 tests after regular traditional Chinese medicine and western medicine treatments. After administration of Pien-Tze-Huang and cessation of previous treatments, SARS-CoV-2 tests results of the patients turned and remained negative. We believe the finding will contribute to a better understanding of atypical COVID-19 cases and hope to offer a potential therapy. Since this is a preliminary case series, larger-scale clinical trials are warranted.
自2019年12月以来，2019冠状病毒病（COVID-19）已在全球迅速传播，成为全球大流行疾病。已发现COVID-19的非典型病例，表现为恢复期严重急性呼吸综合征冠状病毒2（SARS-CoV-2）检测结果持续呈阳性。这些病例增加了COVID-19预防和治疗的难度。在此，我们报告5例COVID-19患者，他们在接受常规中西医治疗后SARS-CoV-2检测结果持续呈阳性。在给予片仔癀并停止先前治疗后，患者的SARS-CoV-2检测结果转阴并保持阴性。我们相信这一发现将有助于更好地了解非典型COVID-19病例，并希望提供一种潜在的治疗方法。由于这是一个初步的病例系列，有必要进行更大规模的临床试验。
