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完全腹腔镜治疗肠结核合并肠穿孔:全球文献首例报道及简要综述

Totally laparoscopic treatment of intestinal tuberculosis complicated with bowel perforation: The first case report in worldwide literature with a brief review.

作者信息

Di Buono Giuseppe, Vella Roberta, Amato Giuseppe, Romano Giorgio, Rodolico Vito, Saverino Marta, De Lisi Giovanni, Romano Giorgio, Buscemi Salvatore, Agrusa Antonino

机构信息

Department of Surgical, Oncological and Oral Sciences, University of Palermo, Palermo, Italy.

Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialities (PROMISE), University of Palermo, Palermo, Italy.

出版信息

Front Surg. 2022 Aug 9;9:956124. doi: 10.3389/fsurg.2022.956124. eCollection 2022.

Abstract

INTRODUCTION

Bowel perforation is a relatively rare presentation of abdominal tuberculosis, whose diagnosis is challenging but fundamental to minimize morbidity and mortality. Laparoscopy is considered an effective modality for diagnosis, but its role in surgical treatment is still not established. We reported the first worldwide case of totally laparoscopic treatment of intestinal tuberculosis complicated with bowel perforation.

CASE PRESENTATION

A 30-year-old man with a history of weight loss, preceded by 2 years of nonproductive cough, was admitted to the Infectious Disease Department with a presumed diagnosis of tuberculosis. A microbiological culture test confirmed the diagnosis, and the patient undertook quadruple antituberculous therapy. During hospitalization, he presented sudden abdominal pain, fever, and vomit. An abdominal CT scan showed small bowel perforation with granulomatous reaction. Laparoscopy was performed and revealed a 2 cm perforation on the medium ileum. Small bowel resection and totally intracorporeal side-to-side anastomosis were performed. No complication occurred until a clinical follow-up of 2 months.

CONCLUSION

In consideration of the increasing incidence of intestinal TB in both underdeveloped and Western countries, the diagnosis of this pathology should be taken into account in high-risk patients. Probably, the diagnostic challenges and emergency settings of intestinal TB with perforation and peritonitis, together with the lack of standardized guidelines regarding surgical management, make the use of laparoscopy apparently arduous, but the known advantages of laparoscopy and its technical feasibility should make it a conceivable option for the treatment of complicated cases.

摘要

引言

肠穿孔是腹部结核相对少见的一种表现形式,其诊断具有挑战性,但对于降低发病率和死亡率至关重要。腹腔镜检查被认为是一种有效的诊断方式,但其在手术治疗中的作用仍未明确。我们报道了全球首例完全腹腔镜治疗合并肠穿孔的肠结核病例。

病例介绍

一名30岁男性,有体重减轻史,之前有2年干咳史,因疑似结核病入住感染科。微生物培养检查确诊后,患者接受了四联抗结核治疗。住院期间,他突然出现腹痛、发热和呕吐。腹部CT扫描显示小肠穿孔伴肉芽肿反应。进行了腹腔镜检查,发现回肠中段有一个2厘米的穿孔。实施了小肠切除及完全体内端侧吻合术。直到2个月的临床随访期均未发生并发症。

结论

鉴于肠结核在欠发达国家和西方国家的发病率均不断上升,高危患者应考虑对这种疾病进行诊断。肠结核合并穿孔和腹膜炎的诊断挑战及紧急情况,再加上缺乏关于手术管理的标准化指南,使得腹腔镜检查的应用显然具有难度,但腹腔镜检查已知的优势及其技术可行性应使其成为治疗复杂病例的一个可行选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/947d/9395922/a5156547342a/fsurg-09-956124-g001.jpg

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