Strates B S, Hofmann L M
Pharmatherapeutica. 1987;5(1):57-61.
A randomized study was carried out in 195 out-patients, due to undergo large bowel radiological examination, to compare the efficacy, patient acceptance and incidence of side-effects of a commercially-available bowel evacuant kit (magnesium citrate oral solution, phenolphthalein tablets and a bisacodyl suppository) and castor oil with enemas. Overall evaluation by a radiologist of large bowel preparation, based on post-barium evacuation X-rays, was satisfactory in more than 98% of patients while bowel cleanliness, as determined by the ability to detect a 1 cm lesion, was adequate in 95% of patients using either preparation. Patient acceptance was in favour of the commercial preparation in that fewer patients using it found the procedure uncomfortable or indicated a preference for another evacuant than did those prepared with castor oil and enemas.
对195名因需接受大肠放射学检查的门诊患者进行了一项随机研究,以比较一种市售肠道排空套件(枸橼酸镁口服溶液、酚酞片和比沙可啶栓剂)与蓖麻油加灌肠剂在疗效、患者接受度和副作用发生率方面的差异。根据钡剂排空后的X线片,放射科医生对大肠准备情况的总体评估显示,超过98%的患者情况令人满意;而通过能否检测到1厘米病变来确定的肠道清洁度方面,使用这两种制剂的患者中,95%的患者肠道清洁度足够。患者接受度方面,市售制剂更受青睐,因为使用该制剂的患者中,觉得该程序不舒服或表示更喜欢另一种排空剂的患者比使用蓖麻油加灌肠剂准备的患者更少。