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用新鲜稳定可乐籽提取物对大鼠进行亚慢性治疗所产生的行为影响。

Behavioral effects resulting from sub-chronic treatment of rats with extract of fresh stabilized cola seeds.

作者信息

Scotto G, Maillard C, Vion-Dury J, Balansard G, Jadot G

出版信息

Pharmacol Biochem Behav. 1987 Apr;26(4):841-5. doi: 10.1016/0091-3057(87)90619-8.

DOI:10.1016/0091-3057(87)90619-8
PMID:3602040
Abstract

The aim of our study was to compare the effects of a sub-chronic treatment with fresh cola seed extract and pure caffeine in the male rat. The activity tests (open-field) and reactivity (tail-tap, resistance to capture), show that fresh cola has an effect on behavior similar to that of caffeine. However, the effects of cola are more gradual than those of caffeine. Furthermore, cola administration leads to an increase in the fall latency observed during the grasping test. These results suggest that the fresh cola seed has both psychostimulating properties similar to those of caffeine, and an original effect on muscular tonus.

摘要

我们研究的目的是比较用新鲜可乐籽提取物和纯咖啡因对雄性大鼠进行亚慢性治疗的效果。活动测试(旷场试验)和反应性测试(轻拍尾巴、抗抓捕)表明,新鲜可乐对行为的影响与咖啡因类似。然而,可乐的影响比咖啡因更为渐进。此外,给予可乐会导致在抓握测试中观察到的跌落潜伏期增加。这些结果表明,新鲜可乐籽具有与咖啡因类似的精神刺激特性,并且对肌肉紧张度有独特影响。

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