Borges J M, Charles H C, Lee C M, Smith R T, Cunha-Vaz J G, Goldberg M F, Tso M O
Retina. 1987 Spring;7(1):46-57.
Chorioretinal lesions produced by dye laser photocoagulation were examined on normal monkey retinas, using angiographic and histopathologic techniques. Retinal burns produced by green (514 nm), yellow (577 nm), orange (600 nm), and red (630 nm) laser lights were placed in the posterior pole between the fovea and the major vascular arcades. When examined histopathologically 24 hours after treatment, greater damage to the inner retina and deep choroid was noted with the red laser light than with the green, yellow and orange laser lights. These differences were not detectable 31 days after treatment. There were no appreciable acute differences among the lesions caused by green, yellow and orange irradiation. Laser light at four wavelengths of the orange spectrum (590, 595, 600, and 605 nm) produced comparable chorioretinal destruction in the juxtafoveal zone when examined 24 hours and 31 days after treatment. Retinal arterioles and venules treated with yellow (577 nm) and orange (600 nm) laser light demonstrated endothelial and pericytic cell damage. Changes in the outer retina, pigment epithelium, and choriocapillaris were also present beneath the photocoagulated vessels.
利用血管造影和组织病理学技术，对正常猴视网膜上染料激光光凝产生的脉络膜视网膜病变进行了检查。用绿色（514纳米）、黄色（577纳米）、橙色（600纳米）和红色（630纳米）激光在黄斑中央凹和主要血管弓之间的后极部造成视网膜烧伤。治疗后24小时进行组织病理学检查时，发现红色激光对视网膜内层和脉络膜深层的损伤比绿色、黄色和橙色激光更严重。治疗后31天未检测到这些差异。绿色、黄色和橙色激光照射造成的病变之间没有明显的急性差异。治疗后24小时和31天检查时，橙色光谱四个波长（590、595、600和605纳米）的激光在黄斑旁区域造成了相当的脉络膜视网膜破坏。用黄色（577纳米）和橙色（600纳米）激光治疗的视网膜小动脉和小静脉显示出内皮细胞和周细胞损伤。在光凝血管下方的视网膜外层、色素上皮和脉络膜毛细血管也出现了变化。
