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原发性自发性气胸无肺大疱的手术治疗。

Surgical Management of Primary Spontaneous Pneumothorax Without Lung Bullae.

机构信息

Department of Thoracic Surgery, University and Hospital Trust - Borgo Trento, Verona, Italy.

Department of Thoracic Surgery, University and Hospital Trust - Borgo Trento, Verona, Italy.

出版信息

J Surg Res. 2022 Dec;280:241-247. doi: 10.1016/j.jss.2022.07.026. Epub 2022 Aug 23.

Abstract

INTRODUCTION

Primary spontaneous pneumothorax (PSP) is a relatively common disease. Different studies have been published but lung resection, when no emphysema-like changes (ELC) are detected, is unclear. The aim of our study is to retrospectively investigate the role of lung resection of the apex of the lung in patients with no ELC.

METHODS

This is a retrospective multicenter study of 516 patients who underwent surgical treatment of PSP with no ELC between January 2007 and December 2017. Patients were divided into two groups: pleurodesis alone group, only mechanical pleurodesis performed (53 patients), and apical resection group, apical resection of the lung and mechanical pleurodesis performed (463 patients). The following were the primary end points considered: recurrence rate and perioperative complications; the following were the secondary end points considered: length of stay, chest tube removal, residual pleural space, prolonged air leak, and reoperation rate.

RESULTS

No differences were found in the baseline and operative characteristics of the two groups. Both primary end points were statistically different: recurrence rate (15.1% versus 6.5%, P = 0.023) and perioperative complications (18.9% versus 7.3%, P = 0.004). Among secondary end points length of stay (6.94 versus 5.55, P = 0.033) and prolonged air leak (15.1% versus 4.3%, P = 0.001) were statistically different. On multivariate analysis, lung resection emerged as a protective factor for recurrence (hazard ratio 0.182, P < 0.001).

CONCLUSIONS

In our experience, apical lung resection in patients without ELC may reduce recurrence rate and perioperative complications when compared with pleurodesis alone.

摘要

简介

原发性自发性气胸(PSP)是一种相对常见的疾病。已经发表了不同的研究结果,但在没有肺气肿样改变(ELC)的情况下进行肺切除术尚不清楚。我们的研究目的是回顾性调查无 ELC 患者行肺尖部切除术的作用。

方法

这是一项回顾性多中心研究,纳入了 2007 年 1 月至 2017 年 12 月期间接受无 ELC 的 PSP 外科治疗的 516 例患者。患者分为两组:单纯胸膜固定术组,仅行机械性胸膜固定术(53 例);肺尖部切除术组,行肺尖部切除术和机械性胸膜固定术(463 例)。主要终点包括:复发率和围手术期并发症;次要终点包括:住院时间、胸腔引流管拔除时间、残余胸腔空间、持续性漏气和再次手术率。

结果

两组患者的基线和手术特征无差异。两个主要终点均有统计学差异:复发率(15.1%比 6.5%,P=0.023)和围手术期并发症(18.9%比 7.3%,P=0.004)。次要终点中,住院时间(6.94 比 5.55,P=0.033)和持续性漏气(15.1%比 4.3%,P=0.001)有统计学差异。多变量分析显示,肺切除术是复发的保护因素(风险比 0.182,P<0.001)。

结论

根据我们的经验,与单纯胸膜固定术相比,无 ELC 患者行肺尖部切除术可能会降低复发率和围手术期并发症发生率。

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