Center for Cardiac Arrest, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Remissgatan 4, S-22185 Lund, Sweden; Team CPR, Practicum Clinical Skills Centre, Region Skåne, Jan Waldenströms gata 24, S-20502 Malmö, Sweden.
Center for Cardiac Arrest, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Remissgatan 4, S-22185 Lund, Sweden; Department of Cardiology, Skåne University Hospital, Entrégatan 7, S-221 85 Lund, Sweden.
Resuscitation. 2022 Oct;179:131-140. doi: 10.1016/j.resuscitation.2022.08.012. Epub 2022 Aug 24.
To analyze the impact of a time-gain selective, first-responder dispatch system on the presence of a shockable initial rhythm (SIR), return of spontaneous circulation (ROSC) and 30-day survival after out-of-hospital cardiac arrest (OHCA).
A retrospective observational study comprising OHCA registry data and dispatch data in the Skåne Region, Sweden (2010-2018). Data were categorized according to dispatch procedures, two ambulances (AMB-only) versus two ambulances and firefighter first-responders (DUAL-dispatch), based on the dispatcher's estimation of a time-gain. Dual dispatch was sub-categorized by arrival of first vehicle (first-responder or ambulance). Logistic regressions were used, additionally with groups matched (1:1) for age, sex, location, witnessed event, bystander cardiopulmonary resuscitation and ambulance response time. Adjusted and conditional odds-ratios (aOR, cOR) with 95% confidence intervals (CI) are presented.
Of 3,245 eligible cases, 43% were DUAL-dispatches with first-responders first on scene (FR-first) in 72%. Despite a five-minute median reduction in response time in the FR-first group, no association with SIR was found (aOR 0.83, 95%CI 0.64-1.07) nor improved 30-day survival (aOR 1.03, 95%CI 0.72-1.47). A positive association between ROSC and the FR-first group (aOR 1.25, 95%CI 1.02-1.54) disappeared in the matched analysis (cOR 1.12, 95%CI 0.87-1.43). Time to first monitored rhythm was 7:06 minutes in the FR-first group versus 3:01 in the combined AMB-only/AMB-first groups.
In this time-gain selective first-responder dispatch system, a shorter response time was not associated with increased SIR, improved ROSC rate or survival. Process measures differed between the study groups which could account for the observed findings and requires further investigation.
分析采用时间增益选择、第一响应者调度系统对院外心脏骤停(OHCA)后是否存在可除颤初始节律(SIR)、自主循环恢复(ROSC)和 30 天生存率的影响。
这是一项回顾性观察性研究,纳入了瑞典斯科讷地区 OHCA 登记处数据和调度数据(2010-2018 年)。根据调度员对时间增益的估计,将数据分为两种调度程序:仅派出 2 辆救护车(AMB-only)与派出 2 辆救护车和消防急救员(DUAL-dispatch)。根据第一响应者或救护车到达现场的情况,将双重调度进一步细分为亚类。采用逻辑回归,另外还进行了年龄、性别、地点、目击事件、旁观者心肺复苏和救护车反应时间匹配(1:1)的组间比较。呈现调整后和条件比值比(aOR,cOR)及其 95%置信区间(CI)。
在 3245 例合格病例中,43%为 DUAL 调度,其中 72%有第一响应者先到达现场(FR-first)。尽管 FR-first 组的反应时间中位数缩短了 5 分钟,但与 SIR 无关(aOR 0.83,95%CI 0.64-1.07),30 天生存率也没有改善(aOR 1.03,95%CI 0.72-1.47)。在匹配分析中,ROSC 与 FR-first 组之间的正相关关系(aOR 1.25,95%CI 1.02-1.54)消失(cOR 1.12,95%CI 0.87-1.43)。FR-first 组首次监测到节律的时间为 7:06 分钟,而 AMB-only/AMB-first 组为 3:01 分钟。
在这种采用时间增益选择、第一响应者调度系统中,反应时间缩短与增加 SIR、提高 ROSC 率或生存率无关。研究组之间的过程指标存在差异,这可能是导致观察到的结果的原因,需要进一步调查。