Department of Chemistry, National Institute of Technology Nagaland, Chumoukedima, Dimapur, Nagaland, 797103, India.
Advanced Materials Group, Materials Sciences and Technology Division, CSIR-North East Institute of Science and Technology, Jorhat, Assam, 785006, India.
Sci Rep. 2022 Aug 26;12(1):14613. doi: 10.1038/s41598-022-18780-x.
The catalytic activity of 1D 2-Picolinic acid based Cu (II) coordination polymer (CP1) in click reaction was evaluated to generate 1,4-disubstituted 1,2,3-triazoles selectively. The CP1 catalyst loading of 2 mol% was applied successfully in the reaction for primary azides with diverse functionalities of terminal alkynes in green solvent (EG/H2O). Moreover, the one-pot, multicomponent click reaction involving benzyl bromide, sodium azide, and phenylacetylene was also catalyzed by CP1. The findings show that 1D 2-Picolinic acid based Cu (II) coordination polymer catalytic systems are highly efficient for green click triazoles synthesis. DFT calculation supported the plausible mechanism involved in the CP1 catalyzed click reaction.
1D 2-吡啶甲酸基 Cu（II）配位聚合物（CP1）在点击反应中的催化活性被评估，以选择性地生成 1,4-取代的 1,2,3-三唑。CP1 催化剂的负载量为 2 mol%，成功应用于具有不同末端炔烃官能团的伯叠氮化物的反应中，在绿色溶剂（EG/H2O）中进行。此外，CP1 还催化了涉及苄基溴、叠氮化钠和苯乙炔的一锅多组分点击反应。研究结果表明，1D 2-吡啶甲酸基 Cu（II）配位聚合物催化体系在绿色点击三唑合成中具有高效性。DFT 计算支持了 CP1 催化点击反应中涉及的合理机制。
