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左心室罕见的心内膜黏液瘤酷似纤维瘤。

A rare left ventricular cardiac myxoma mimicking fibroma.

机构信息

Department of Stomatology, The First Hospital of Jilin University, Changchun, 130021, Jilin, China.

Department of Orthopedic Surgery, The Second Hospital of Jilin University, Changchun, 130021, Jilin, China.

出版信息

J Cardiothorac Surg. 2022 Aug 26;17(1):207. doi: 10.1186/s13019-022-01968-7.

DOI:10.1186/s13019-022-01968-7
PMID:36028867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9414120/
Abstract

BACKGROUND

In most cases, it is not difficult to differentiate common left ventricular (LV) cardiac myxomas from fibromas because they are different disease entities and have different imaging findings. Herein, we present a case of a tumor with histological characteristics of a LV cardiac myxoma even though its imaging and macroscopical views were similar to that of fibroma.

CASE PRESENTATION

A 65-year-old woman was admitted to the hospital with chest tightness and palpitations which persisted for 2 years. Transthoracic echocardiogram and transesophageal echocardiography revealed a 23 mm × 8 mm, polyp-like-shaped, homogeneous, firm, solitary, mobile and solitary LV mass, which protruded into the left atrium during systole, resulting in mild mitral regurgitation. LV contrast-enhanced echocardiography revealed that there was little contrast agent filling in the LV mass. To further clarify the nature of the mass, non-enhanced and contrast-enhanced coronary computed tomography (CT) angiograms showed a 19 mm × 8 mm relatively homogeneous low density with punctate calcifications mass and no significant enhancement. Thus, we preoperatively diagnosed her condition as a LV fibroma and performed excision of the tumor under cardiopulmonary by-pass by using port-access approach through right mini-thoracotomy. The postoperative pathological diagnosis of the tumor was in fact a LV myxoma.

CONCLUSIONS

LV cardiac myxomas mimicking fibroma makes diagnosis difficult, and sonographers should be aware of this imaging changes.

摘要

背景

在大多数情况下,区分常见的左心室(LV)心脏黏液瘤和纤维瘤并不困难,因为它们是不同的疾病实体,具有不同的影像学表现。在此,我们报告了一个肿瘤的病例,其组织学特征为左心室心脏黏液瘤,尽管其影像学和大体表现类似于纤维瘤。

病例介绍

一名 65 岁女性因胸闷和心悸持续 2 年而入院。经胸超声心动图和经食管超声心动图显示一个 23mm×8mm、息肉样、均匀、坚实、单发、活动、单发的 LV 肿块,在收缩期突入左心房,导致轻度二尖瓣反流。LV 对比增强超声心动图显示 LV 肿块内造影剂填充较少。为了进一步明确肿块的性质,非增强和增强冠状动脉计算机断层扫描(CT)血管造影显示一个 19mm×8mm 相对均匀的低密度伴点状钙化肿块,无明显强化。因此,我们术前诊断为 LV 纤维瘤,并通过右小开胸经端口通路在心肺旁路下行肿瘤切除术。肿瘤的术后病理诊断实际上是左心室黏液瘤。

结论

左心室心脏黏液瘤表现为纤维瘤样,使诊断变得困难,超声医师应该意识到这种影像学变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a89a/9414120/f7d79f6703cb/13019_2022_1968_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a89a/9414120/b12c71318783/13019_2022_1968_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a89a/9414120/caca7df1aba8/13019_2022_1968_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a89a/9414120/f7d79f6703cb/13019_2022_1968_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a89a/9414120/b12c71318783/13019_2022_1968_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a89a/9414120/caca7df1aba8/13019_2022_1968_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a89a/9414120/f7d79f6703cb/13019_2022_1968_Fig3_HTML.jpg

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Asymptomatic Left Atrial Myxoma Treated With Minimally Invasive Surgical Approach.采用微创外科手术方法治疗无症状性左心房黏液瘤。
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Adv Anat Pathol. 2020 Nov;27(6):380-384. doi: 10.1097/PAP.0000000000000275.
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Risk factors of embolism for the cardiac myxoma patients: a systematic review and metanalysis.心脏黏液瘤患者栓塞风险因素的系统评价和荟萃分析。
BMC Cardiovasc Disord. 2020 Jul 25;20(1):348. doi: 10.1186/s12872-020-01631-w.
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Pulmonary embolism as the initial manifestation of right atrial myxoma: A case report and review of the literature.肺栓塞作为右心房黏液瘤的首发表现:一例病例报告及文献复习
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Acute blindness as a presenting sign of left atrial myxoma in a pediatric patient: A case report and literature review.急性失明作为小儿患者左心房黏液瘤的首发症状:一例病例报告及文献综述
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