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动态超声评估新鲜冷冻标本臀部中的填充物和生物刺激剂。

Dynamic ultrasound evaluation of body fillers and biostimulators in the buttocks of fresh-frozen specimen.

机构信息

Hospital das Clínicas da faculdade de Medicina da USP, São Paulo, Brazil.

Private Practice in Dermatology, São Paulo, Brazil.

出版信息

J Cosmet Dermatol. 2022 Nov;21(11):5621-5627. doi: 10.1111/jocd.15333. Epub 2022 Sep 20.

Abstract

BACKGROUND

Ultrasound imaging is a useful tool to study the injection of fillers and biostimulators in the body.

OBJECTIVE

Sonographically evaluate real-time injections of fillers and biostimulators and describe their behavior in the subcutaneous tissue of the buttocks of fresh-frozen specimen.

METHODS

injection of two brands of high-density hyaluronic acid (HA), one brand of calcium hydroxyapatite (CaHA), one brand of hybrid injectable (CaHa + HA), one brand of polycaprolactone (PCL) and three brands of poly-l-lactic acid (PLLA) were performed in the subcutaneous tissue of the gluteal region under ultrasonography visualization on a fresh-frozen specimen. Videos during injection and static images immediately after injection were obtained. The sonographic aspects of the substances and their dispersion and interaction with the surrounding tissues were described.

RESULTS

Real-time ultrasound showed different dispersion patterns of the two brands of HA, CaHA, hybrid injectable (CaHa + HA) and the three brands of PLLA. The sonographic aspects among the brands of PLLA were also different.

CONCLUSIONS

The dynamic ultrasound evaluation of the injection of HA, CaHA, hybrid injectable (CaHa + HA), PCL and PLLA in a fresh-frozen specimen shed some light on their aspects and dispersion pattern in the buttock. If these patterns are confirmed in further studies in vivo, there will be a positive impact on the selection and development of safer and more effective techniques to enhance buttock contour.

摘要

背景

超声成像是研究填充物和生物刺激剂在体内注射的有用工具。

目的

实时评估填充物和生物刺激剂的超声注射,并描述其在新鲜冷冻标本臀部皮下组织中的行为。

方法

在新鲜冷冻标本的超声可视化下,在臀部的皮下组织中注射两种品牌的高密度透明质酸(HA)、一种品牌的钙羟磷灰石(CaHA)、一种品牌的混合可注射(CaHa+HA)、一种品牌的聚己内酯(PCL)和三种品牌的聚左旋乳酸(PLLA)。注射过程中的视频和注射后立即的静态图像。描述了物质及其与周围组织的分散和相互作用的超声表现。

结果

实时超声显示了两种品牌的 HA、CaHA、混合可注射(CaHa+HA)和三种品牌的 PLLA 的不同分散模式。PLLA 品牌之间的超声表现也不同。

结论

对新鲜冷冻标本中 HA、CaHA、混合可注射(CaHa+HA)、PCL 和 PLLA 的注射进行动态超声评估,阐明了它们在臀部的外观和分散模式。如果这些模式在进一步的体内研究中得到证实,将对选择和开发更安全、更有效的增强臀部轮廓技术产生积极影响。

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