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利用组学技术成功实现肉类生产动物的“同一健康”理念。

The successful use of -omic technologies to achieve the 'One Health' concept in meat producing animals.

机构信息

Division of Animal Physiology and Immunology, TUM School of Life Sciences, Technical University of Munich, Freising, Germany.

Division of Animal Physiology and Immunology, TUM School of Life Sciences, Technical University of Munich, Freising, Germany; Eurofins Medigenomix Forensik GmbH, Anzinger Straße 7a, 85560 Ebersberg, Germany.

出版信息

Meat Sci. 2022 Nov;193:108949. doi: 10.1016/j.meatsci.2022.108949. Epub 2022 Aug 20.

Abstract

Human health and wellbeing are closely linked to healthy domestic animals, a vital wildlife, and an intact ecosystem. This holistic concept is referred to as 'One Health'. In this review, we provide an overview of the potential and the challenges for the use of modern -omics technologies, especially transcriptomics and proteomics, to implement the 'One Health' idea for food-producing animals. These high-throughput studies offer opportunities to find new potential molecular biomarkers to monitor animal health, detect pharmacological interventions and evaluate the wellbeing of farm animals in modern intensive livestock systems.

摘要

人类健康和福祉与健康的家养动物、重要的野生生物和完整的生态系统密切相关。这一整体概念被称为“同一健康”。在这篇综述中,我们概述了现代组学技术(特别是转录组学和蛋白质组学)在实施面向食品生产动物的“同一健康”理念方面的潜力和挑战。这些高通量研究为寻找新的潜在分子生物标志物提供了机会,以监测动物健康、检测药物干预并评估现代集约化畜牧系统中农场动物的福利。

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