Groopman J E
Semin Oncol. 1987 Jun;14(2 Suppl 3):1-6.
Associated with the acquired immune deficiency syndrome (AIDS) is a wide spectrum of opportunistic infections and secondary cancers. Foremost among the cancers is an aggressive form of Kaposi's sarcoma (KS) that was rarely seen in the United States before 1981. The pathogenesis of this AIDS-related KS is obscure, and its prognosis is mainly related to the patient's immune status and history of opportunistic infections. Treatment modalities include local or regional radiotherapy, cytotoxic chemotherapy, and interferon therapy. Other cancers associated with AIDS include non-Hodgkin's lymphomas that are typically high-grade, diffuse B cell neoplasms occurring at unusual sites, frequently in the brain. Management of the patient with an AIDS-associated neoplasm requires a multidisciplinary team that includes specialists in infectious diseases, dermatology, radiotherapy, psychiatry, and nutrition, as well as oncology.
获得性免疫缺陷综合征（艾滋病）会引发一系列机会性感染和继发性癌症。其中最主要的癌症是一种侵袭性卡波西肉瘤（KS），1981年以前在美国很少见。这种与艾滋病相关的KS的发病机制尚不清楚，其预后主要与患者的免疫状态和机会性感染史有关。治疗方式包括局部或区域放疗、细胞毒性化疗和干扰素治疗。与艾滋病相关的其他癌症包括非霍奇金淋巴瘤，通常为高级别、弥漫性B细胞肿瘤，发生在不寻常的部位，常见于脑部。对患有艾滋病相关肿瘤的患者进行管理需要一个多学科团队，其中包括传染病、皮肤病学、放疗、精神病学和营养学专家，以及肿瘤学专家。
