Triozzi P L
Division of Hematology and Oncology, Ohio State University.
Oncology (Williston Park). 1991 Sep;5(9 Suppl):25-30.
We have made progress in the therapy of AIDS-related malignancies, although it is obvious that our treatment strategies, at present, are not--by any measure--satisfactory. Effective treatment should take into account the pathogenesis and etiology of the malignancy; immune and performance status of the patient; the rate of progress of the tumor; the presence or risk of developing life-threatening opportunistic infections; associated hematologic, neurologic, pulmonary, and gastrointestinal abnormalities; the toxicities of treatment; and, most importantly, the patient's desire for treatment. Aggressive supportive measures must be used. With optimal management, it should be increasingly possible to improve the outcome of patients with AIDS-related malignancies.
我们在艾滋病相关恶性肿瘤的治疗方面取得了进展，尽管目前很明显，无论从哪方面衡量，我们的治疗策略都不尽如人意。有效的治疗应考虑到恶性肿瘤的发病机制和病因；患者的免疫和身体状况；肿瘤的进展速度；发生危及生命的机会性感染的情况或风险；相关的血液学、神经学、肺部和胃肠道异常；治疗的毒性；以及最重要的，患者对治疗的意愿。必须采取积极的支持措施。通过优化管理，越来越有可能改善艾滋病相关恶性肿瘤患者的治疗结果。
