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避免小儿脑积水行脑脊液分流术的治疗策略和挑战。

Treatment Strategies and Challenges to Avoid Cerebrospinal Fluid Shunting for Pediatric Hydrocephalus.

机构信息

Department of Neurosurgery and Children's Medical Center, Nara Medical University.

出版信息

Neurol Med Chir (Tokyo). 2022 Sep 15;62(9):416-430. doi: 10.2176/jns-nmc.2022-0100. Epub 2022 Aug 27.

Abstract

Treatment for pediatric hydrocephalus aims not only to shrink the enlarged ventricle morphologically but also to create an intracranial environment that provides the best neurocognitive development and to deal with various treatment-related problems over a long period of time. Although the primary diseases that cause hydrocephalus are diverse, the ventricular peritoneal shunt has been introduced as the standard treatment for several decades. Nevertheless, complications such as shunt infection and shunt malfunction are unavoidable; the prognosis of neurological function is severely affected by such factors, especially in newborns and infants.In recent years, treatment concepts have been attempted to avoid shunting, mainly in the context of pediatric cases. In this review, the current role of neuroendoscopic third ventriculostomy for noncommunicating hydrocephalus is discussed and a new therapeutic concept for post intraventricular hemorrhagic hydrocephalus in preterm infants is documented. To avoid shunt placement and achieve good neurodevelopmental outcomes for pediatric hydrocephalus, treatment modalities must be developed.

摘要

儿童脑积水的治疗不仅旨在使扩大的脑室在形态上缩小,而且要创造一个颅内环境,为患儿提供最佳的神经认知发育,并在很长一段时间内处理各种与治疗相关的问题。虽然引起脑积水的主要疾病多种多样,但脑室-腹腔分流术已被引入作为几十年的标准治疗方法。然而,分流感染和分流故障等并发症是不可避免的;这些因素严重影响神经功能的预后,尤其是在新生儿和婴儿中。近年来,人们尝试避免分流的治疗概念,主要是在儿科病例中。在这篇综述中,讨论了神经内镜第三脑室造瘘术在非交通性脑积水的当前作用,并记录了一种新的治疗早产儿脑室内出血后脑积水的治疗概念。为了避免分流,并为小儿脑积水实现良好的神经发育结果,必须开发治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf21/9534569/408b7e7ebef3/1349-8029-62-0416-g001.jpg

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