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建模随机诊断对沙特阿拉伯 COVID-19 传播的影响。

Modeling the effect of random diagnoses on the spread of COVID-19 in Saudi Arabia.

机构信息

Department of Mathematics, King Abdulaziz University, Jeddah, Saudi Arabia.

出版信息

Math Biosci Eng. 2022 Jul 8;19(10):9792-9824. doi: 10.3934/mbe.2022456.

Abstract

Saudi Arabia was among the countries that attempted to manage the COVID-19 pandemic by developing strategies to control the epidemic. Lockdown, social distancing and random diagnostic tests are among these strategies. In this study, we formulated a mathematical model to investigate the impact of employing random diagnostic tests to detect asymptomatic COVID-19 patients. The model has been examined qualitatively and numerically. Two equilibrium points were obtained: the COVID-19 free equilibrium and the COVID-19 endemic equilibrium. The local and global asymptotic stability of the equilibrium points depends on the control reproduction number R. The model was validated by employing the Saudi Ministry of Health COVID-19 dashboard data. Numerical simulations were conducted to substantiate the qualitative results. Further, sensitivity analysis was performed on R to scrutinize the significant parameters for combating COVID-19. Finally, different scenarios for implementing random diagnostic tests were explored numerically along with the control strategies applied in Saudi Arabia.

摘要

沙特阿拉伯是试图通过制定控制疫情的策略来管理 COVID-19 大流行的国家之一。这些策略包括封锁、社交距离和随机诊断测试。在这项研究中,我们制定了一个数学模型来研究采用随机诊断测试来检测无症状 COVID-19 患者的影响。该模型已经进行了定性和数值研究。得到了两个平衡点:COVID-19 无病平衡点和 COVID-19 地方病平衡点。平衡点的局部和全局渐近稳定性取决于控制繁殖数 R。该模型通过使用沙特卫生部 COVID-19 仪表板数据进行了验证。进行了数值模拟以证实定性结果。此外,对 R 进行了敏感性分析,以仔细检查对抗 COVID-19 的重要参数。最后,数值研究了实施随机诊断测试的不同方案以及沙特阿拉伯应用的控制策略。

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