University of Khartoum Faculty of Medicine, obstetrics and gynecology.
Department of obstetrics and gynecology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Afr Health Sci. 2022 Mar;22(1):164-171. doi: 10.4314/ahs.v22i1.21.
Grand multiparity is a major health problem that leads to adverse maternal and perinatal outcomes. We aimed to assess the maternal and perinatal outcomes of grand multiparity.
A case-control study was conducted in Saad Abualila Hospital, Khartoum, Sudan from February to December 2019. The cases were grand multiparous (≥ 5 deliveries) women. The controls were women with low parity (multiparous women who delivered two to four times). Maternal and perinatal characteristics were compared between the two groups. Logistic regression analysis was performed.
There was a significant association between grand multiparity and higher maternal age (adjusted odds ratio [AOR]=1.19, 95% confidence interval [CI]=1.16-1.23), lower education level (AOR=3.38, 95% CI=2.49-5.58) and lower antenatal care attendance (AOR=1.73, 95% CI=1.02-2.92). Grand multiparous women were at increased risk for Anemia (AOR=1.48, 95% CI=1.08-2.03), diabetes mellitus (AOR=10.61, 95% CI=4.89-23.00), caesarean delivery (AOR=1.87, 95% CI=1.40-2.48), preterm birth (AOR=1.90, 95% CI=1.37-2.62) and admission to the neonatal intensive care unit (AOR=3.8, 95% CI=1.95-7.75).
Grand multiparity was associated with poor maternal and neonatal outcomes. Development of a national health program addressing family planning, health education and improvement of antenatal, intrapartum and neonatal care are needed.
多胎妊娠是一种主要的健康问题,可导致不良的母婴围产期结局。本研究旨在评估多胎妊娠的母婴围产期结局。
本研究为 2019 年 2 月至 12 月在苏丹喀土穆的 Saad Abualila 医院进行的病例对照研究。病例为多胎妊娠(≥5 次分娩)的妇女,对照为多胎妊娠(分娩两次至四次的妇女)。比较两组产妇和围产儿的特征。采用 logistic 回归分析。
多胎妊娠与产妇年龄较大(调整后的优势比 [AOR]=1.19,95%置信区间 [CI]=1.16-1.23)、教育程度较低(AOR=3.38,95%CI=2.49-5.58)和产前保健就诊率较低(AOR=1.73,95%CI=1.02-2.92)显著相关。多胎妊娠妇女发生贫血(AOR=1.48,95%CI=1.08-2.03)、糖尿病(AOR=10.61,95%CI=4.89-23.00)、剖宫产(AOR=1.87,95%CI=1.40-2.48)、早产(AOR=1.90,95%CI=1.37-2.62)和新生儿重症监护病房入住率(AOR=3.8,95%CI=1.95-7.75)的风险增加。
多胎妊娠与母婴不良结局相关。需要制定一项国家卫生计划,解决计划生育、健康教育以及改善产前、分娩和新生儿护理的问题。