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网络荟萃分析传统中医运动疗法对原发性高血压患者降压效果的影响。

Network Meta-Analysis of the Antihypertensive Effect of Traditional Chinese Exercises on Patients with Essential Hypertension.

机构信息

College of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, China.

Students' Affairs Department, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China.

出版信息

J Healthc Eng. 2022 Aug 17;2022:9419037. doi: 10.1155/2022/9419037. eCollection 2022.

DOI:10.1155/2022/9419037
PMID:36032544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9402382/
Abstract

BACKGROUND

In recent years, traditional Chinese exercises (TCEs) have been gradually used to reduce the blood pressure levels of patients with essential hypertension. However, there are several types of TCEs, and there is no comparative study on the antihypertensive effects of various TCEs in patients with essential hypertension.

OBJECTIVE

The objective is to compare the therapeutic effects of Taijiquan (TJQ), Baduanjin (BDJ), Wuqinxi (WQX), and Yijinjing (YJJ) on essential hypertension and provide a reference for clinical treatment and scheme optimization.

METHODS

The China National Knowledge Infrastructure (CNKI), Wanfang, China Scientific Journal Database, China Biology Medicine database (CBM), PubMed, Embase, Cochrane Library, and Web of Science databases were searched to collect all randomized controlled trials (RCTs) of TCEs in the treatment of essential hypertension. The search time was from the establishment of each database to November 2021. After data extraction and quality evaluation, the network meta-analysis was performed with Stata 16.0 and ADDIS 1.16.8.

RESULTS

Finally, 45 RCTs involving 3864 patients were included. Network meta-analysis showed that YJJ had the best effect in reducing systolic blood pressure, and the difference was statistically significant [MD = -14.27, 95% CI = (-20.53∼-8.08), < 0.05]. The best probability ranking was YJJ (=0.736) > TJQ (=0.203) > WQX (=0.059) > BDJ (=0.002). In terms of reducing diastolic blood pressure, the treatment effect of YJJ was the best, and the difference was statistically significant [MD = -7.77, 95% CI (-12.19∼-3.33), < 0.05]. The best probability ranking was YJJ (=0.702) > TJQ (=0.178) > WQX (=0.095) > BDJ (=0.025).

CONCLUSION

The results showed that TCEs significantly reduced systolic and diastolic blood pressure compared with the control group, and YJJ might be the best choice. However, a larger sample, multicenter, double-blinded, high-quality RCTs are needed to make clear conclusions.

摘要

背景

近年来,中医传统功法(TCEs)已逐渐用于降低原发性高血压患者的血压水平。然而,TCEs 有多种类型,目前尚无关于各种 TCEs 对原发性高血压降压效果的比较研究。

目的

旨在比较太极拳(TJQ)、八段锦(BDJ)、五禽戏(WQX)和易筋经(YJJ)治疗原发性高血压的疗效,为临床治疗及方案优化提供参考。

方法

计算机检索中国知网(CNKI)、万方、中国生物医学文献数据库(CBM)、PubMed、Embase、Cochrane 图书馆、Web of Science 数据库,收集 TCEs 治疗原发性高血压的随机对照试验(RCT),检索时限均为各数据库建库至 2021 年 11 月。提取资料并评价质量后,采用 Stata 16.0 和 ADDIS 1.16.8 软件进行网状 Meta 分析。

结果

最终纳入 45 项 RCT,共计 3864 例患者。网状 Meta 分析结果显示,YJJ 降低收缩压的效果最佳,差异有统计学意义[MD=-14.27,95% CI=(-20.53∼-8.08), < 0.05]。最佳概率排序为 YJJ(=0.736)>TJQ(=0.203)>WQX(=0.059)>BDJ(=0.002)。在降低舒张压方面,YJJ 的疗效最佳,差异有统计学意义[MD=-7.77,95% CI=(-12.19∼-3.33), < 0.05]。最佳概率排序为 YJJ(=0.702)>TJQ(=0.178)>WQX(=0.095)>BDJ(=0.025)。

结论

结果表明,TCEs 可显著降低收缩压和舒张压,与对照组相比差异有统计学意义,YJJ 可能是最佳选择。但仍需要开展更大样本、多中心、双盲、高质量 RCT 以得出更明确的结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9402382/a2c2ae159584/JHE2022-9419037.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9402382/eb0474d00880/JHE2022-9419037.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9402382/7913b65ad0a8/JHE2022-9419037.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9402382/3049f026fb4e/JHE2022-9419037.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9402382/a2c2ae159584/JHE2022-9419037.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9402382/eb0474d00880/JHE2022-9419037.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9402382/7913b65ad0a8/JHE2022-9419037.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9402382/3049f026fb4e/JHE2022-9419037.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9402382/a2c2ae159584/JHE2022-9419037.004.jpg

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