Department of Medicine and Medical Specialty, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Spain.
Immune System Diseases-Rheumatology and Oncology Service, University Hospital "Príncipe de Asturias", Alcalá de Henares, Madrid, Spain.
Biomed Res Int. 2017;2017:2356346. doi: 10.1155/2017/2356346. Epub 2017 Sep 20.
The aim of this study was to summarize evidence on the effectiveness of therapeutic exercise in Fibromyalgia Syndrome.
Studies retrieved from the Cochrane Plus, PEDro, and Pubmed databases were systematically reviewed. Randomized controlled trials and meta-analyses involving adults with fibromyalgia were included. The primary outcomes considered in this systematic review were pain, global well-being, symptoms of depression, and health-related quality of life.
Effects were summarized using standardized mean differences with 95% confidence intervals using a random effects model. This study provides strong evidence that physical exercise reduces pain (-1.11 [95% CI] -1.52; -0.71; overall effect < 0.001), global well-being (-0.67 [95% CI] -0.89, -0.45; < 0.001), and symptoms of depression (-0.40 [95% CI] -0.55, -0.24; < 0.001) and that it improves both components of health-related quality of life (physical: 0.77 [95% CI] 0.47; 1.08; < 0.001; mental: 0.49 [95% CI] 0.27; 0.71; < 0.001).
This study concludes that aerobic and muscle strengthening exercises are the most effective way of reducing pain and improving global well-being in people with fibromyalgia and that stretching and aerobic exercises increase health-related quality of life. In addition, combined exercise produces the biggest beneficial effect on symptoms of depression.
本研究旨在总结治疗性运动在纤维肌痛综合征中的有效性证据。
系统综述检索了 Cochrane Plus、PEDro 和 Pubmed 数据库中的研究。纳入了涉及纤维肌痛成人的随机对照试验和荟萃分析。本系统评价考虑的主要结局为疼痛、整体幸福感、抑郁症状和健康相关生活质量。
使用随机效应模型，使用标准化均数差值和 95%置信区间总结效应。本研究提供了强有力的证据表明，体育锻炼可减轻疼痛（-1.11 [95%CI] -1.52；-0.71；总体效应<0.001）、整体幸福感（-0.67 [95%CI] -0.89，-0.45；<0.001）和抑郁症状（-0.40 [95%CI] -0.55，-0.24；<0.001），并改善健康相关生活质量的两个组成部分（身体：0.77 [95%CI] 0.47；1.08；<0.001；精神：0.49 [95%CI] 0.27；0.71；<0.001）。
本研究得出结论，有氧运动和肌肉强化运动是减轻纤维肌痛患者疼痛和提高整体幸福感的最有效方法，伸展和有氧运动可提高健康相关生活质量。此外，联合运动对抑郁症状产生最大的有益影响。
