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发展中国家普遍新生儿听力筛查的挑战——一把双刃剑

Challenges of Universal Newborn Hearing Screening in a Developing Country-a Double-Edged Sword.

作者信息

Jacob Jaise, Kurien Mary, Kumar Pradeep, Krishnan Lalitha

机构信息

Department of ENT, Pondicherry Institute of Medical Science, Puducherry, India.

Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Aug;74(Suppl 1):395-401. doi: 10.1007/s12070-020-02170-8. Epub 2020 Sep 28.

Abstract

Objective to implement Universal Neonatal Hearing Screening (UNHS) in a tertiary academic hospital and identify associated risk factors. Prospective study. Screening tests with Otoacoustic Emissions (OAE) were done among newborns, prior to hospital discharge. In babies who fail OAE twice, Brain Response Audiometry (BERA) was done, failing which they were referred to higher ENT center for repeat testing and hearing rehabilitation. A total 2323 babies were admitted in the neonatal unit during the study period. Only 773 babies (a third) could be screened for the first OAE, two thirds being lost to study right at inception!! Among the 773 neonates, in the "at risk" group of 301 neonates, 31(10%) and in the "not at risk" group of 472 neonates, 30 (6%) were lost to follow up respectively. The occurrence of hearing loss in this study population was 1.3 per 1000. Risk factors were noted in 38.9% of this subgroup with occurrence of hearing loss in "at risk" group being 3.32 per 1000. The implementation of UNHS in a developing country like India, has multiple challenges including infrastructural and non-compliance to follow up. In the meantime, the possibility of compromising 'at-risk" neonates, who are significantly more prone to hearing loss, both neonatal and delayed onset, is an additional grave reality which needs deep considerationin this Herculean task of attaining "universality".

摘要

目的是在一家三级学术医院实施新生儿听力普遍筛查(UNHS)并确定相关风险因素。前瞻性研究。在新生儿出院前,用耳声发射(OAE)进行筛查测试。对于两次OAE测试未通过的婴儿,进行脑干听觉诱发电位(BERA)测试,若BERA测试未通过,则将他们转诊至上级耳鼻喉中心进行重复测试和听力康复。在研究期间,新生儿病房共收治了2323名婴儿。只有773名婴儿(三分之一)能够接受首次OAE筛查,三分之二在一开始就失访了!!在773名新生儿中,301名处于“高危”组的新生儿中有31名(10%)失访,472名处于“非高危”组的新生儿中有30名(6%)失访。该研究人群中听力损失的发生率为每1000人中有1.3例。在这个听力损失亚组中,38.9%的人存在风险因素,“高危”组中听力损失的发生率为每1000人中有3.32例。在印度这样的发展中国家实施UNHS面临多重挑战,包括基础设施问题和随访不依从。与此同时,在这项实现“普遍性”的艰巨任务中,忽视那些明显更容易出现新生儿期和迟发性听力损失的“高危”新生儿的可能性是另一个严峻的现实,需要深入思考。

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