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五年内发生的巨大左房肉瘤以发音障碍为首发症状

Dysphonia as a Presenting Symptom of a Giant Left Atrial Sarcoma Developing within Five Years.

作者信息

Elbayomi Mohamed, Nooh Ehab, Weyand Michael, Agaimy Abbas, Harig Frank

机构信息

Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.

Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.

出版信息

Thorac Cardiovasc Surg Rep. 2022 Aug 24;11(1):e50-e53. doi: 10.1055/s-0042-1751028. eCollection 2022 Jan.

DOI:10.1055/s-0042-1751028
PMID:36032935
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9402287/
Abstract

An 83-year-old woman presented with a new onset of dyspnea and dysphonia. Physical examination revealed no abnormalities. Computerized tomography, bidimensional echocardiography, and cardiac magnetic resonance confirmed the presence of a cardiac mass in the left atrium. Surgical resection was uneventful and showed the origin of the mass in the ostium of the left inferior pulmonary vein. Histological evaluation revealed undifferentiated pleomorphic sarcoma with myxoid features. This case highlights the importance of considering cardiac neoplasms as a rare differential diagnosis, including rare and misleading clinical presentations.

摘要

一名83岁女性出现新发呼吸困难和声音嘶哑。体格检查未发现异常。计算机断层扫描、二维超声心动图和心脏磁共振成像证实左心房存在心脏肿块。手术切除过程顺利，显示肿块起源于左下肺静脉口。组织学评估显示为具有黏液样特征的未分化多形性肉瘤。该病例强调了将心脏肿瘤作为罕见鉴别诊断的重要性，包括罕见且具有误导性的临床表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/bd12d72d6304/10-1055-s-0042-1751028-i220426crc-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/ddf1ad0a6905/10-1055-s-0042-1751028-i220426crc-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/3e78f3a9adab/10-1055-s-0042-1751028-i220426crc-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/6242d84f1ee9/10-1055-s-0042-1751028-i220426crc-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/1791577b7583/10-1055-s-0042-1751028-i220426crc-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/41e109ae0722/10-1055-s-0042-1751028-i220426crc-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/bd12d72d6304/10-1055-s-0042-1751028-i220426crc-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/ddf1ad0a6905/10-1055-s-0042-1751028-i220426crc-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/3e78f3a9adab/10-1055-s-0042-1751028-i220426crc-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/6242d84f1ee9/10-1055-s-0042-1751028-i220426crc-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/1791577b7583/10-1055-s-0042-1751028-i220426crc-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/41e109ae0722/10-1055-s-0042-1751028-i220426crc-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1295/9402287/bd12d72d6304/10-1055-s-0042-1751028-i220426crc-6.jpg

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本文引用的文献

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Primary Cardiac Malignancies: The Need for a Multidisciplinary Approach and the Role of the Cardio-Oncologist.原发性心脏恶性肿瘤：多学科方法的必要性及心脏肿瘤学家的作用
J Am Coll Cardiol. 2020 May 12;75(18):2348-2351. doi: 10.1016/j.jacc.2020.03.046.
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Improved Outcomes With the Evolution of a Neoadjuvant Chemotherapy Approach to Right Heart Sarcoma.右心肉瘤新辅助化疗方法的演变带来更好的治疗结果。
Ann Thorac Surg. 2017 Jul;104(1):90-96. doi: 10.1016/j.athoracsur.2016.10.054. Epub 2017 Feb 9.
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Malignant tumors of the heart.心脏恶性肿瘤
罕见病例报告：左心房肉瘤阻塞左心室流入道。
J Clin Med. 2023 Oct 11;12(20):6460. doi: 10.3390/jcm12206460.
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Case of left atrial myxoid sarcoma with lung metastases presented as a cardiogenic shock: a case report and literature review.以心源性休克为表现的左房黏液样肉瘤伴肺转移病例：一例报告及文献复习
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Primary cardiac sarcomas: a retrospective study of the French Sarcoma Group.原发性心脏肉瘤：法国肉瘤研究组的回顾性研究。
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Clinical classification of cardiovascular tumors and tumor-like lesions, and its incidences.心血管肿瘤及肿瘤样病变的临床分类及其发病率。
Gen Thorac Cardiovasc Surg. 2013 Aug;61(8):435-47. doi: 10.1007/s11748-013-0214-8. Epub 2013 Mar 5.
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Primary intimal (spindle cell) sarcoma of the heart: a case report and review of the literature.心脏原发性内膜（梭形细胞）肉瘤：一例报告并文献复习
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