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基于卷积神经网络的 MRI 图像脑肿瘤分割研究。

Research on Segmentation of Brain Tumor in MRI Image Based on Convolutional Neural Network.

机构信息

Department of Radiology, The First People's Hospital of Jingmen City, Hubei, China.

Neurosurgery, The First People's Hospital of Jingmen City, Hubei, China.

出版信息

Biomed Res Int. 2022 Aug 5;2022:7911801. doi: 10.1155/2022/7911801. eCollection 2022.

Abstract

Brain tumors are the brain diseases with the highest mortality and prevalence, and magnetic resonance imaging has high-resolution and multiparameter. As the basis for realizing the quantitative analysis of brain tumors, automatic segmentation plays a vital role in diagnosis and treatment. A new network model is proposed to improve the accuracy of convolutional neural network segmentation of brain tumor regions and control the parameter space scale of the network model. The model first uses a convolutional layer composed of a series of 3D convolution filters to construct a backbone network for feature learning of input 3D MRI image blocks. Then, a pyramid structure constructed by a 3D convolutional layer is designed to extract and fuse features of tumor lesions and context information of different scales and then classify the fused feature at the voxel level to obtain segmentation results. Finally, a conditional random field is used to postprocess segmentation results for structured refinement. By designing massive ablation experiments to analyze the sensitivity of the essential modules of the comparison network, the results confirm that our method can better solve the problems faced by the traditional fully connected convolutional neural network.

摘要

脑肿瘤是死亡率和发病率最高的脑部疾病,磁共振成像是一种具有高分辨率和多参数的技术。作为实现脑肿瘤定量分析的基础,自动分割在诊断和治疗中起着至关重要的作用。本文提出了一种新的网络模型,以提高卷积神经网络对脑肿瘤区域分割的准确性,并控制网络模型的参数空间尺度。该模型首先使用由一系列 3D 卷积滤波器组成的卷积层构建骨干网络,用于对输入的 3D MRI 图像块进行特征学习。然后,设计了一个由 3D 卷积层构成的金字塔结构,用于提取和融合肿瘤病变的特征以及不同尺度的上下文信息,然后在体素水平上对融合的特征进行分类,以获得分割结果。最后,使用条件随机场对分割结果进行后处理,进行结构化细化。通过设计大量的消融实验来分析对比网络的关键模块的敏感性,结果证实了我们的方法可以更好地解决传统全连接卷积神经网络所面临的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4525/9410817/fb98060d1d4f/BMRI2022-7911801.001.jpg

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