创伤性脑损伤患者的性别差异：来自 1 级创伤中心的回顾性研究。
Gender Discrepancy in Patients with Traumatic Brain Injury: A Retrospective Study from a Level 1 Trauma Center.
机构信息
Clinical Research, Trauma & Vascular Surgery, Hamad General Hospital, Doha, Qatar.
Clinical Medicine, Weill Cornell Medical College, Doha, Qatar.
出版信息
Biomed Res Int. 2022 Aug 18;2022:3147340. doi: 10.1155/2022/3147340. eCollection 2022.
OBJECTIVES
The objective of this study is to explore the gender discrepancy in patients with traumatic brain injury (TBI).
METHODS
A retrospective analysis of Qatar Trauma Registry (QTR) was conducted among patients (age ≥14y) who were hospitalized with TBI. Data were collected and analyzed based on the gender and age.
RESULTS
Over 5 years (2014-2019), 9, 309 trauma patients (90% males and 10% females) were admitted to the trauma center. Of these, 1, 620 (17.4%) patients were hospitalized with TBI (94% males and 6% females). Motor vehicle crash was the main mechanism of injury (MOI) in females, and fall from height was predominant among males. Subdural hematoma (SDH) was the more frequent type of TBI in both genders, but it was more prevalent in male patients ≥55 years. Injury severity score, Glasgow coma scale, and head abbreviated injury score were comparable between males and females. The length of stay in the ICU and hospital and mortality were similar in both genders. However, mortality was higher among males ≥55 years when compared to 14-54 years within the same gender (21% vs. 12%, = 0.002). The crude and adjusted odds ratio did not show that gender is a significant predictor of mortality among TBI patients.
CONCLUSIONS
Although the incidence and MOI of TBI show significant differences between male and female patients, the severity and outcomes are comparable.
目的
本研究旨在探讨创伤性脑损伤（TBI）患者的性别差异。
方法
对卡塔尔创伤登记处（QTR）中年龄≥14 岁因 TBI 住院的患者进行回顾性分析。根据性别和年龄收集和分析数据。
结果
在 5 年期间（2014-2019 年），9309 名创伤患者（90%为男性，10%为女性）被收入创伤中心。其中，1620 名（17.4%）患者因 TBI 住院（94%为男性，6%为女性）。女性的主要损伤机制是机动车事故，而男性主要损伤机制是高处坠落伤。硬膜下血肿（SDH）是两性中更常见的 TBI 类型，但在≥55 岁的男性患者中更为常见。损伤严重程度评分、格拉斯哥昏迷评分和头部简明损伤评分在男性和女性之间相似。男性和女性在 ICU 和医院的住院时间和死亡率相似。然而，与同性别 14-54 岁的患者相比，≥55 岁的男性患者的死亡率更高（21%比 12%，=0.002）。粗比和调整比值比均表明，性别不是 TBI 患者死亡的显著预测因素。
结论
尽管男性和女性 TBI 的发生率和损伤机制存在显著差异，但严重程度和结局相当。
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