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优化结肠镜检查的肠道准备:一项针对中国人群的横断面研究。

Optimizing bowel preparation for colonoscopy: A cross-sectional study of the Chinese population.

作者信息

Luo Li, Liu Yuan, Zhang Lingling, Lai Yihuan, Li Yansheng, Liu Kejia, Gong Houwu, Jiang Dapeng, Wang Erchuan

机构信息

Department of Gastroenterology, West Hospital, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Front Public Health. 2022 Aug 12;10:953441. doi: 10.3389/fpubh.2022.953441. eCollection 2022.

DOI:10.3389/fpubh.2022.953441
PMID:36033785
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9412238/
Abstract

BACKGROUND

The quality of bowel preparation is an important factor in the success of colonoscopy. However, the quality of bowel preparation is often affected by multiple factors. The main objective of this study was to explore the specific factors that affect the quality of bowel preparation.

METHODS

Patients were consecutively recruited from the gastroenterology department in Union Hospital, Tongji Medical College, Huazhong University of Science and Technology in Wuhan from May 2018 to December 2018. All patients were undergoing colonoscopy. Bowel preparation was evaluated by the Ottawa Bowel preparation Scale (OBPS) and all patients were categorized into 2 groups according to the OBPS. Multivariate analysis was conducted to identify the factors associated with bowel preparation quality.

RESULTS

A total of 910 patients were included in the analysis with an average age of 48.62 ± 13.57 years. Patient source ( < 0.001) and the preparation method ( = 0.029) were correlated with OBPS adequacy. In addition, after stratified by age, preparation method ( = 0.022) was a significant factor among patients under 50 years old; whereas waiting time ( = 0.005) was a significant factor among patients over 50 years old.

CONCLUSION

Bowel preparation should be tailored based on the age of the patients to determine the most appropriate plan, including the most appropriate waiting time and the most appropriate purgative combination. Doctors should also focus more on the quality of bowel preparation in inpatients, who are more likely than outpatients to have an inadequate bowel preparation.

摘要

背景

肠道准备质量是结肠镜检查成功的重要因素。然而,肠道准备质量常受多种因素影响。本研究的主要目的是探讨影响肠道准备质量的具体因素。

方法

2018年5月至2018年12月,连续招募华中科技大学同济医学院附属协和医院胃肠科正在接受结肠镜检查的患者。采用渥太华肠道准备量表(OBPS)评估肠道准备情况,并根据OBPS将所有患者分为两组。进行多因素分析以确定与肠道准备质量相关的因素。

结果

共纳入910例患者进行分析,平均年龄为48.62±13.57岁。患者来源(<0.001)和准备方法(=0.029)与OBPS充分性相关。此外,按年龄分层后,准备方法(=0.022)在50岁以下患者中是一个显著因素;而等待时间(=0.005)在50岁以上患者中是一个显著因素。

结论

应根据患者年龄调整肠道准备方案,以确定最合适的计划,包括最合适的等待时间和最合适的泻药组合。医生还应更加关注住院患者的肠道准备质量,住院患者比门诊患者更易出现肠道准备不充分的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93e1/9412238/902026a20020/fpubh-10-953441-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93e1/9412238/902026a20020/fpubh-10-953441-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93e1/9412238/902026a20020/fpubh-10-953441-g0001.jpg

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Effect of oral simethicone on the quality of colonoscopy: A systematic review and meta-analysis of randomized controlled trials.口服二甲硅油对结肠镜检查质量的影响:一项随机对照试验的系统评价和荟萃分析。
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When should we perform colonoscopy to increase the adenoma detection rate?我们应该在什么时候进行结肠镜检查以提高腺瘤检出率?
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A Comparative Clinical Study of a Novel Pre-colonoscopy Bowel Capsule Preparation Against Two Commercially Available Liquid Preparations.一种新型结肠镜检查前肠道胶囊制剂与两种市售液体制剂的比较临床研究。
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