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[支气管哮喘患者血液中酸溶性代谢产物——中分子的浓度]

[Concentration of acid-soluble metabolites--middle molecules in the blood of bronchial asthma patients].

作者信息

Amatuni V G, Pogosian E Sh, Budagian A L

出版信息

Ter Arkh. 1987;59(3):36-8.

PMID:3603386
Abstract

The level of the derivatives of protein and lipid metabolism increases in the blood of patients with bronchial asthma (BA) and chronic asthmatic bronchitis (CAB), in particular that of peroxide radicals, the products of lipid peroxidation (LPO), the fraction of acid soluble metabolites--average mass molecules (AMM). The blood acquires unusual toxicity. The content of AMM in the blood of BA and CAB patients shows correlation with LPO and is in direct relation to severity of clinical symptoms. The removal of toxic products from the body by hemosorption promotes clinical remission and a decrease in AMM and LPO levels.

摘要

支气管哮喘(BA)和慢性哮喘性支气管炎(CAB)患者血液中蛋白质和脂质代谢衍生物水平升高,尤其是过氧化物自由基、脂质过氧化(LPO)产物、酸溶性代谢产物部分——平均质量分子(AMM)。血液获得异常毒性。BA和CAB患者血液中AMM的含量与LPO相关,且与临床症状的严重程度直接相关。通过血液吸附从体内清除有毒产物可促进临床缓解,并降低AMM和LPO水平。

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