Memetov K A, Trofimov V K, Boĭkov M P, Ipatov A I, Makoeva L D
Ter Arkh. 1987;59(3):39-42.
The authors presented the results of a combined study of 100 patients with infectious-allergic bronchial asthma. During and after attacks of asphyxia parameters of central hemodynamics and pressure in the lesser circulation system were defined. The patients were divided into 3 groups with relation to cardiac output values. An increase in cardiac output and pressure elevation in the right ventricle were noted in the 1st group, the values of pressure of pulmonary artery obstruction slightly raised. The absence of a marked increase in cardiac output was observed in the 2nd group, however pressure in the arterial system of the lesser circulation increased in the period of asphyxia. A decrease in cardiac output and an increase in pressure in the system of the pulmonary artery were noted in the patients of the 3rd group during asthmatic attacks. Such changes in the hemodynamics of the patients with bronchial asthma during attacks of asphyxia led to an idea of a possible favorable reaction of the cardiovascular system in the 1st group, maximum effort of compensatory capabilities in the 2nd group and depletion of reserve function of the cardiovascular system in the 3rd group. An elevation of pressure of pulmonary artery obstruction in the patients of the 2nd and 3rd groups confirmed a possibility of development not only of right but also left ventricular circulatory insufficiency during an attack of bronchial asthma.
作者介绍了对100例感染性过敏性支气管哮喘患者的联合研究结果。在窒息发作期间及之后，测定了中心血流动力学参数和小循环系统压力。根据心输出量值将患者分为3组。第1组患者的心输出量增加，右心室压力升高，肺动脉阻塞压力值略有升高。第2组未观察到心输出量明显增加，但在窒息期小循环动脉系统压力升高。第3组患者在哮喘发作期间心输出量减少，肺动脉系统压力升高。支气管哮喘患者在窒息发作期间血流动力学的这些变化，使人想到第1组心血管系统可能有良好反应，第2组代偿能力发挥到最大，第3组心血管系统储备功能耗竭。第2组和第3组患者肺动脉阻塞压力升高，证实了支气管哮喘发作期间不仅可能发生右心室循环功能不全，也可能发生左心室循环功能不全。
