Department of Paediatric Endocrinology, Diabetology & Metabolism, University Children's Hospital, Inselspital, Bern, Switzerland.
Department of BioMedical Research, Bern University Hospital and University of Bern, Bern, Switzerland.
J Diabetes Res. 2022 Aug 17;2022:3170558. doi: 10.1155/2022/3170558. eCollection 2022.
Lower HbA1c targets and increasingly complex diabetes management with substantially increasing costs dominate today's type 1 diabetes therapy in children and adolescents.
To evaluate metabolic control in children and adolescents with type 1 diabetes and assess associated factors, evaluate determinants for frequency of healthcare contacts, and compare actual with historical data.
This cross-sectional observational study collected data on 178 children and adolescents with type 1 diabetes treated at the University Children's Hospital in Bern.
Mean HbA1c was 7.9% (63 mmol/mol), 33.1% (59/178) of children reached the target of HbA1c < 7.5% (<59 mmol/mol), and 18.0% (32/178) had an HbA1c value < 7.0% (<53 mmol/mol). Compared to historical data, stable HbA1c levels appeared with a doubled proportion of individuals using insulin pumps. Metabolic control was worse with a longer duration of diabetes and younger age at diagnosis but better when parents came from a Western European country. Age at the consultation, use of diabetes technology and native language influenced the number of healthcare contacts. Younger patients, patients using CSII, and patients without an official Swiss language as mother tongue had more consultations with a healthcare professional than older and native language individuals.
The metabolic targets in childhood and adolescent type 1 diabetes are still unmet despite a shift towards more technology. Our study documents a higher demand for support and supervision in specific patient groups. An investment to increase healthcare contacts could help combat the increase in total diabetes cost and significantly improve metabolic control.
较低的糖化血红蛋白(HbA1c)目标和日益复杂的糖尿病管理,以及成本的大幅增加,主导了当今儿童和青少年 1 型糖尿病的治疗。
评估儿童和青少年 1 型糖尿病患者的代谢控制情况,并评估相关因素,评估医疗保健接触频率的决定因素,并将实际数据与历史数据进行比较。
这项横断面观察性研究收集了伯尔尼大学儿童医院 178 名 1 型糖尿病儿童和青少年的数据。
平均 HbA1c 为 7.9%(63mmol/mol),33.1%(59/178)的儿童达到了 HbA1c<7.5%(<59mmol/mol)的目标,18.0%(32/178)的儿童 HbA1c 值<7.0%(<53mmol/mol)。与历史数据相比,使用胰岛素泵的个体比例增加了一倍,HbA1c 水平更加稳定。糖尿病病程较长和诊断时年龄较小的患者代谢控制较差,但父母来自西欧国家的患者则较好。就诊时的年龄、糖尿病技术的使用和母语会影响医疗保健接触的次数。年轻患者、使用 CSII 的患者和母语不是瑞士官方语言的患者比年长和母语为瑞士官方语言的患者与医疗保健专业人员的咨询次数更多。
尽管向更多技术转变,但儿童和青少年 1 型糖尿病的代谢目标仍未达到。我们的研究记录了特定患者群体对支持和监督的更高需求。增加医疗保健接触的投资有助于控制总糖尿病成本的增加,并显著改善代谢控制。