Hunan Province Key Laboratory of Tumor Cellular & Molecular Pathology, Cancer Research Institute, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.
School of Nursing, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.
Comput Math Methods Med. 2022 Aug 17;2022:4463294. doi: 10.1155/2022/4463294. eCollection 2022.
NOSH-Aspirin, which is generated from NO, HS, and aspirin, affects a variety of essential pathophysiological processes, including anti-inflammatory, analgesic, antipyretic, antiplatelet, and anticancer properties. Although many people acknowledge the biological significance of NOSH-Aspirin and its therapeutic effects, the mechanism of action of NOSH-Aspirin and its regulation of tissue levels remains obscure. This is in part due to its chemical and physical features, which make processing and analysis difficult. This review focuses on the biological effects of NOSH-Aspirin and provides a comprehensive analysis to elucidate the mechanism underlying its disease-protective benefits.
NOSH-阿司匹林由 NO、HS 和阿司匹林生成，影响多种基本病理生理过程，具有抗炎、镇痛、解热、抗血小板和抗癌作用。尽管许多人认识到 NOSH-阿司匹林的生物学意义及其治疗效果，但 NOSH-阿司匹林的作用机制及其对组织水平的调节仍不清楚。这在一定程度上是由于其化学和物理特性，使得处理和分析变得困难。本综述重点介绍了 NOSH-阿司匹林的生物学作用，并进行了全面分析，以阐明其疾病保护益处的机制。
