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登革热病毒与严重急性呼吸综合征冠状病毒2共同感染动态:非洲国家面临的新威胁。

Dengue virus and SARS-CoV-2 Co-infection dynamics: An emerging threat among African countries.

作者信息

Oladipo Habeebullah Jayeola, Rabiu Ismail, Tajudeen Yusuf Amuda

机构信息

Department of Microbiology, Faculty of Life Sciences, University of Ilorin, P.M.B. 1515, Ilorin, 240003, Nigeria.

Faculty of Pharmaceutical Sciences, University of Ilorin, P.M.B. 1515, Ilorin, 240003, Nigeria.

出版信息

Ann Med Surg (Lond). 2022 Oct;82:104398. doi: 10.1016/j.amsu.2022.104398. Epub 2022 Aug 22.

Abstract

The rising circulation of the vector borne disease such as dengue fever amidst the COVID-19 pandemic in African countries is on the rise, which pose a significant public health threat. In this article, we discussed the co-infection of dengue virus (DENV) (the causative agent of dengue fever) and SARS-CoV-2 (the causative agents of COVID-19) as well as the associated risk factors involved. Our review highlights that the continuous increase in the incidence and disease mortality from the co-infection of dengue Virus and SARS-CoV-2 is as result of inadequate surveillance and limited testing centers. Second, the overlapping clinical features and indistinguishable symptoms from both infections is a major challenge. Third, lack of scientific prudence among stakeholders has played a significant impact on how to contain these diseases. Therefore, there is a need to reassess research priorities in understanding the risk factors involved from the coinfection. Also, the development of accurate point-of-care diagnostics for COVID-19 and dengue fever coupled with community-based health intervention programs is highly essential for control.

摘要

在非洲国家的新冠疫情期间,登革热等媒介传播疾病的传播正在增加,这构成了重大的公共卫生威胁。在本文中,我们讨论了登革热病毒(DENV,登革热的病原体)和严重急性呼吸综合征冠状病毒2(SARS-CoV-2,新冠病毒的病原体)的共同感染以及相关的风险因素。我们的综述强调,登革热病毒和SARS-CoV-2共同感染导致的发病率和疾病死亡率持续上升,是由于监测不足和检测中心有限。其次,两种感染的临床特征重叠和症状难以区分是一个重大挑战。第三,利益相关者缺乏科学审慎对如何控制这些疾病产生了重大影响。因此,有必要重新评估研究重点,以了解共同感染所涉及的风险因素。此外,开发针对新冠病毒和登革热的准确即时诊断方法以及基于社区的健康干预计划对于控制疫情至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b2/9516388/1c7a36f86f99/gr1.jpg

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