• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

马缨丹(马缨丹属马缨丹)毒素的分离与部分纯化。

Isolation and partial purification of Lantana (Lantana camara L.) toxins.

作者信息

Sharma O P, Dawra R K, Makkar H P

出版信息

Toxicol Lett. 1987 Jul;37(2):165-72. doi: 10.1016/0378-4274(87)90153-6.

DOI:10.1016/0378-4274(87)90153-6
PMID:3603590
Abstract

A partially purified toxin fraction and lantadene A were obtained from Lantana camara L. leaves by batch extraction, column chromatography and fractional crystallization. Toxicity was tested in guinea pigs. The total number of chemical entities in the partially purified toxin preparation was 7, the 2 major ones being lantadene A and lantadene B. Lantadene A was nontoxic in itself. Likewise, another fraction containing lantadene A, lantadene B and 3 more components with higher polarity was found to be nontoxic. The toxic component(s) are different from lantadene A/B but appear to resemble them very closely.

摘要

通过分批萃取、柱色谱法和分级结晶从马缨丹叶中获得了部分纯化的毒素组分和马缨丹烯A。在豚鼠身上测试了其毒性。部分纯化的毒素制剂中的化学实体总数为7种,其中2种主要成分是马缨丹烯A和马缨丹烯B。马缨丹烯A本身无毒。同样,另一个含有马缨丹烯A、马缨丹烯B和另外3种极性更高的成分的组分也被发现无毒。有毒成分与马缨丹烯A/B不同,但似乎与它们非常相似。

相似文献

1
Isolation and partial purification of Lantana (Lantana camara L.) toxins.马缨丹(马缨丹属马缨丹)毒素的分离与部分纯化。
Toxicol Lett. 1987 Jul;37(2):165-72. doi: 10.1016/0378-4274(87)90153-6.
2
Toxicity of isolated Lantana (Lantana camara L) constituents to male and female guinea pigs.
Vet Hum Toxicol. 1989 Feb;31(1):10-3.
3
Biological action of lantadene C, a new hepatotoxicant from Lantana camara var. aculeata.马缨丹变种刺马缨丹中的一种新型肝毒素——马缨丹烯C的生物学作用
J Biochem Toxicol. 1992 Summer;7(2):73-9. doi: 10.1002/jbt.2570070204.
4
Lantadene A content and toxicity of the lantana plant (Lantana camara, Linn.) to guinea pigs.马缨丹属植物(马缨丹,林奈)对豚鼠的马缨丹烯A含量及毒性
Toxicon. 1980;18(4):485-8. doi: 10.1016/0041-0101(80)90058-6.
5
Molecular structure, polymorphism, and toxicity of lantadene A, the pentacyclic triterpenoid from the hepatotoxic plant Lantana camara.
J Biochem Toxicol. 1991 Spring;6(1):57-63. doi: 10.1002/jbt.2570060108.
6
Cytotoxic and cell cycle arrest induction of pentacyclic triterpenoides separated from Lantana camara leaves against MCF-7 cell line in vitro.从马缨丹叶中分离出的五环三萜类化合物对MCF-7细胞系的体外细胞毒性及细胞周期阻滞诱导作用
Mol Biol Rep. 2019 Feb;46(1):381-390. doi: 10.1007/s11033-018-4482-3. Epub 2018 Nov 13.
7
Biotransformation of lantadenes, the pentacyclic triterpenoid hepatotoxins of lantana plant, in guinea pig.马缨丹属植物五环三萜类肝毒素马缨丹烯在豚鼠体内的生物转化
Toxicon. 2000 Sep;38(9):1191-202. doi: 10.1016/s0041-0101(99)00204-4.
8
Lantadene A, the active principle of Lantana camara L.; isolation of lantadene B, and the oxygen functions of lantadene A and lantadene B.马缨丹烯A,马缨丹(Lantana camara L.)的活性成分;马缨丹烯B的分离,以及马缨丹烯A和马缨丹烯B的氧官能团
Onderstepoort J Vet Sci Anim Ind. 1948 Mar;23(1-2):233-8.
9
Detoxification of lantana hepatotoxin, lantadene A, using Alcaligenes faecalis.
J Appl Toxicol. 2001 May-Jun;21(3):225-8. doi: 10.1002/jat.746.
10
Filaricidal properties of Lantana camara and Tamarindus indica extracts, and Lantadene A from L. camara against Onchocerca ochengi and Loa loa.马缨丹和罗望子提取物及马缨丹中的 Lantadene A 对盘尾丝虫和罗阿丝虫的杀幼虫作用。
PLoS Negl Trop Dis. 2018 Jun 13;12(6):e0006565. doi: 10.1371/journal.pntd.0006565. eCollection 2018 Jun.

引用本文的文献

1
Lantadene A and boswellic acid isolated from the leaves of L. have the potential to control phytopathogenic species.从该植物叶子中分离出的蓝塔德烯A和乳香酸有控制植物病原菌的潜力。
Heliyon. 2022 Dec 15;8(12):e12216. doi: 10.1016/j.heliyon.2022.e12216. eCollection 2022 Dec.
2
Comparison of lantadenes content and toxicity of different taxa of the lantana plant.比较不同鸡屎藤植物Taxa 的拉坦尼含量和毒性。
J Chem Ecol. 1991 Nov;17(11):2283-91. doi: 10.1007/BF00988008.
3
Cytotoxicity and oral acute toxicity studies of Lantana camara leaf extract.
马缨丹叶提取物的细胞毒性和口服急性毒性研究。
Molecules. 2011 May 3;16(5):3663-74. doi: 10.3390/molecules16053663.
4
Chemical constituents and antifilarial activity of Lantana camara against human lymphatic filariid Brugia malayi and rodent filariid Acanthocheilonema viteae maintained in rodent hosts.马缨丹对在啮齿动物宿主中饲养的人体淋巴丝虫马来布鲁线虫和啮齿动物丝虫旋盘尾丝虫的化学成分及抗丝虫活性
Parasitol Res. 2007 Feb;100(3):439-48. doi: 10.1007/s00436-006-0312-y. Epub 2006 Oct 24.