Chen Fuli, Zeng Shi, Yi Aijiao, Chen Lihua, Zhou Dan, Liu Yushan, Yao Longmei
Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, China.
Department of Ultrasound Diagnosis, The Central Hospital of Yueyang City, Yueyang, China.
Front Cardiovasc Med. 2022 Aug 11;9:858235. doi: 10.3389/fcvm.2022.858235. eCollection 2022.
The purpose of this study is to establish Z-scores models of normal fetal ascending aorta diameter and diameter distensibility.
The maximum systolic diameter (Dmax), minimum diastolic diameter (Dmin), and diameter distensibility of the sinotubular junction were measured and taken as dependent variables in 490 normal fetuses at 18-40 gestational weeks, and gestational age (GA), biparietal diameter (BPD), and femoral length (FL) were taken as independent variables. The data were subjected to regression analysis, and the best-fitting equations for the dependent variables based on the independent variables were determined. The fitting equations were then applied to construct the Z-scores models.
The Dmax, Dmin and Diameter Distensibility in normal fetuses between 18 and 40 weeks of GA could be evaluated by utilizing the Z-scores models. Dmax and Dmin increased significantly with increasing GA, BPD, and FL. Diameter distensibility, assessed as (Dmax-Dmin)/Dmin, decreased significantly with increasing GA, BPD, and FL.
The Z-scores are valuable, and can be utilized as a potent supplement to the conventional approach as they can indirectly reflect the development of fetal ascending aortic elastic property.
本研究旨在建立正常胎儿升主动脉直径和直径扩张性的Z评分模型。
测量490例孕18 - 40周正常胎儿的升主动脉窦管交界处最大收缩期直径（Dmax）、最小舒张期直径（Dmin）和直径扩张性作为因变量，以孕周（GA）、双顶径（BPD）和股骨长度（FL）作为自变量。对数据进行回归分析，确定基于自变量的因变量最佳拟合方程。然后应用拟合方程构建Z评分模型。
利用Z评分模型可评估孕18至40周正常胎儿的Dmax、Dmin和直径扩张性。Dmax和Dmin随GA、BPD和FL的增加而显著增加。以（Dmax - Dmin）/Dmin评估的直径扩张性随GA、BPD和FL的增加而显著降低。
Z评分很有价值，可作为传统方法的有力补充，因为它们可以间接反映胎儿升主动脉弹性特性的发育情况。
